Results 151 to 160 of about 181,535 (188)

Flavonoid Profile, Biological Potentials, and In Silico Approaches of Methanol Extracts on AChE: Amaranthus retroflexus L.

Chemistry &Biodiversity, EarlyView.
ABSTRACT This study investigated the flavonoid compounds and their biological activities in methanol extracts obtained from root, stem, leaf, and flower parts of Amaranthus retroflexus L. Flavonoids in the extracts were characterized for the first time by liquid chromatography–highresolution mass spectrometry (LC–HRMS), and a total of eight flavonoid ...
Bedrettin Selvi, Güler Durmuş, Mustafa Ceylan, Şuheda Yıldırım, Ümit M. Koçyiğit, Ümit Yırtıcı, Volkan Eyüpoğlu   +6 more
wiley   +1 more source

Combination of Probe Electrospray Ionization Mass Spectrometry and Mass Spectrometry Imaging to Analyze Plant Alkaloids in Narcissus tazetta. [PDF]

Mass Spectrom (Tokyo)
Nakagawa K, Iida T, Kobayashi M, Shimma S.   +3 more
europepmc   +1 more source

Antitumor and Cytogenotoxic Activities of Libidibia ferrea Hydroalcoholic Extracts in Murine Breast Carcinoma

Chemistry &Biodiversity, EarlyView.
ABSTRACT Breast cancer is the most prevalent cancer type among women worldwide, and there is a critical need for more effective and safer treatments, especially for aggressive and therapy‐resistant subtypes. Libidibia ferrea, a native plant from Brazil, exhibits anti‐inflammatory, antimicrobial, antioxidant, and antitumor properties.
Diego Pereira de Menezes, Evaldo dos Santos Monção Filho, Atanara Alves de Sousa, João Pedro Alves Damasceno do Lago, Karla Darlianny Mourão Cavalcante, Fernanda Alves de Sousa Cavalcante, Irismara Sousa Silva, Marina Pinto Sanches, Semiramis Jamil Hadad do Monte, Ester Miranda Pereira, Paulo Michel Pinheiro Ferreira, Joao Marcelo de Castro e Sousa, Gerardo Magela Vieira Júnior, Dalton Dittz   +13 more
wiley   +1 more source

Real-Time Monitoring of the Antiseizure Drug Valproic Acid Using a Novel Point-Of-Care Mass Spectrometry. [PDF]

CNS Neurosci Ther
Fang X, Wu J, Hong Y, Bu J, Zhang W, Ouyang Z, Hua W, Mao Y.   +7 more
europepmc   +1 more source

Cytotoxic Activity of Opopanax hispidus (Friv.) Griseb.: Characterization of a New Chalcone‐type Compound

Chemistry &Biodiversity, EarlyView.
ABSTRACT The present study aimed to investigate cytotoxic compounds of Opopanax hispidus (Friv.) Griseb. through in vitro, in silico, and phytochemical analyses. The cytotoxic activity of O. hispidus was evaluated against four different cancer cell lines – lung (A549), breast (MCF‐7), liver (HepG2), and cervix (HeLa) – as well as one healthy cell line (
Kevser Taban, İpek Süntar, Perihan Gürbüz, Esra Emerce, Osman Tugay, Şengül Dilem Doğan, Beyza Hamur, Ahmet Ceyhan Gören   +7 more
wiley   +1 more source

Evaluation of Violacein Metabolic Stability and Metabolite Identification in Human, Mouse, and Rat Liver Microsomes. [PDF]

Pharmaceutics
Calemi DBA, Godoi AB, Minuti G, Neto FC, Hispagnol GF, Pilon AC, Costa JL, Hyslop S, Antunes NJ.   +8 more
europepmc   +1 more source

Rotenoids from the Roots of Vicia faba L. (Fabaceae): Structural Characterization, Cytotoxic Effects, and Molecular Docking

Chemistry &Biodiversity, EarlyView.
ABSTRACT The chemical study of the ethanolic extract from the roots of Vicia faba led to the isolation of two isoflavonoids, alfalone and 8‐O‐methylretusine, as well as a mixture of rotenoids, including clitoriacetal and clitoriacetal B, the latter of which is reported for the first time.
Victor Menezes Sipoloni, João Victor Silva‐Silva, Elthon G. Ferreira, Eric Yoshitaka Lee, João Marcos Batista Junior, Miriam Uemi, Lívia Soman de Medeiros, Paula C. Jimenez, Thiago A. M. Veiga   +8 more
wiley   +1 more source

Unveiling Flavonoid Reactivity: A High-Resolution Mass Spectrometry Journey Through the Silylation of Quercetin. [PDF]

Rapid Commun Mass Spectrom
Ncongwane TB, Madala NE, Ndinteh DT, Smit E.   +3 more
europepmc   +1 more source

Internal Ubiquitin Electrophiles for Covalent Trapping and Inhibition of Deubiquitinases

ChemBioChem, Accepted Article.
The ubiquitin (Ub) system governs vital cellular processes in eukaryotic biology through an intricate network of Ub‐protein interactions. While semisynthetic C‐terminal Ub electrophiles (UbEs) are widely used to study Ub transfer and deubiquitinase (Dub) activity, they are limited to probing the active site while leaving other functionally important ...
Chittaranjan Das, Nipuni M. Pannala, Rishi S. Patel, Abhijith Saseendran Anit, Debapriya Bhattacharya, Kristos Negron Teron, Bryon Drown, Rudi Fasan   +7 more
wiley   +1 more source

Accelerating countermeasure candidate discovery for A-series chemical warfare agent exposure. [PDF]

Proc Natl Acad Sci U S A
Morato NM, Mason KE, Corzett TH, Valdez CA, Alfaro TM, Hok S, Cooks RG, Mayer BP.   +7 more
europepmc   +1 more source