Results 171 to 180 of about 105,942 (260)

Metal‐Ion Regulated Light‐Free Z→E Isomerization of Azobenzene Glycomacrocycle

Chemistry – A European Journal, EarlyView.
Metal ion‐catalyzed Z→E isomerization of photoswitchable azobenzene glycomacrocycle: A new azobenzene‐based glycomacrocycle is capable of forming a 1:1 complex with divalent metal ions in both E‐ and Z‐isomers. The complexes undergo light‐free Z→E isomerization in a timescale spanning from seconds to weeks.
Yang Zhou, Jinbiao Jiao, Mathieu Lordez, Jean‐Yves Salpin, Juan Xie   +4 more
wiley   +1 more source

Ion Mobility-Mass Spectrometry Imaging: Advances in Biomedical Research. [PDF]

BioTech (Basel)
Liu M, Zhang C, Xu L, Rahman MM, Hirayama S, Aramaki S, Baba A, Omagari R, Takahashi Y, Kahyo T, Setou M.   +10 more
europepmc   +1 more source

Control of Gemcitabine Activity With Blue and Red Light

Chemistry – A European Journal, EarlyView.
Treating cancer with chemotherapy is generally associated with many side effects, which can be addressed by selectively releasing the desired drugs with visible light. Sixteen new blue light‐activatable cytostatics were introduced, with the gemcitabine derivative exhibiting ideal properties.
Nils F. Kersten, Konstantin L. Stock, Marius Hyprath, Hannah Weisser, Timo Weinrich, Dieter Steinhilber, Alexander Heckel   +6 more
wiley   +1 more source

Research Progress on the Application of Mass Spectrometry Imaging Technology in Cerebral Disease. [PDF]

Life (Basel)
Qiao Y, Yin J, Lu S, Yin L.
europepmc   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Dynamic Additive Scanning for Precise Control in Electrospray Ionization Mass Spectrometry

ACS Measurement Science Au
I-Ting Wu, Decibel P. Elpa, Hsien-Ning Chien, Pawel L. Urban   +3 more
doaj   +1 more source

Miniaturized chromatography-based lipidomics methods towards single-cell analysis. [PDF]

Anal Bioanal Chem
Rellin KF, Witting M.
europepmc   +1 more source

Charge State Influence on Stability and Isomerism in Dehydrogenated PAHs: Insights from Anthracene, Acridine, and Phenazine

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
The ionization of anthracene, acridine, and phenazine has been explored, along with the removal of one and two hydrogen atoms, to provide valuable information for astrochemists and to understand the behavior of the resulting structures and their electronic reorganization. Abstract In this study, we systematically explored the stability and isomerism of
Khaldia Zghida, Farouk Hamza Reguig, Manuel Alcamí, Al Mokhtar Lamsabhi   +3 more
wiley   +1 more source

Early-stage drug discovery in a new-generation ultrahigh-throughput mass spectrometry platform. [PDF]

Proc Natl Acad Sci U S A
Morato NM, Feng Y, Chen K, Huang KH, Owen A, Caruso JV, Yang B, Kulathunga SC, Mesecar AD, Klumpp-Thomas C, Radujevic A, Godfrey AG, Gardner S, Rudnicki DD, Galbraith M, Gloeckner A, Hajdu C, Pringle SD, Morris M, Balog J, Cooks RG.   +20 more
europepmc   +1 more source

Phase I Metabolism of Novel Phencyclidine Derivative 3‐Cl‐PCP: In Vitro Studies With Pooled Human Liver Microsomes and Investigation of a Post‐Mortem Case

Drug Testing and Analysis, EarlyView.
A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler, Tobias Veit, Thomas Keller, Volker Auwärter   +3 more
wiley   +1 more source