Comprehensive biothreat cluster identification by PCR/electrospray-ionization mass spectrometry. [PDF]
PLoS ONE, 2012 Technology for comprehensive identification of biothreats in environmental and clinical specimens is needed to protect citizens in the case of a biological attack.
Rangarajan Sampath +26 more
doaj +1 more source
Desorption Electrospray Ionization-Mass Spectrometry of Proteins [PDF]
Analytical Chemistry, 2007 Desorption electrospray ionization-mass spectrometry (DESI-MS) was evaluated for the detection of proteins ranging in molecular mass from 12 to 66 kDa. Proteins were uniformly deposited on a solid surface without pretreatment and analyzed with a DESI source coupled to a quadrupole ion trap mass spectrometer.
Richard T. Mayer +4 more
openaire +3 more sources
Is Charge Reduction in ESI Really Necessary? [PDF]
, 2008 The technique of charge reduction electrospray mass spectrometry (CREMS), which can reduce the charge state complexity produced in electrospray ionization (ESI), is ...
Smith, Lloyd M.
core +1 more source
Analysis of Oligonucleotides by Electrospray Ionization Mass Spectrometry [PDF]
Current Protocols in Nucleic Acid Chemistry, 2000 AbstractBecause of the high molecular weights and thermal lability of biomolecules such as nucleic acids and protein, they can be difficult to analyze by mass spectrometry. Such analyses require a “soft” ionization method that is capable of generating intact molecular ions.
Polo, Lenore M., Limbach, Patrick A.
openaire +4 more sources
Structure elucidation of sildenafil analogues in herbal products. [PDF]
, 2004 The structure of unknown compounds present in herbal products was elucidated using liquid chromatography-electrospray ionization-mass spectrometry, direct-infusion electrospray ionization-mass spectrometry, and nuclear magnetic resonance.
Bakker, F +7 more
core +1 more source
Química Nova, 2012 Solutions of [hydroxy(tosyloxy)iodo]benzene (HTIB or Koser's reagent) in acetonitrile were analyzed using high resolution electrospray ionization mass spectrometry (ESI-MS) and electrospray ionization tandem mass spectrometry (ESI-MS/MS) under different ...
Ramon S. Vasconcelos +2 more
doaj +1 more source
False positives and the detection of cyclodextrin inclusion complexes by electrospray mass spectrometry [PDF]
, 1995 The results of previous works that have claimed to detect cyclodextrin inclusion complexes via the “soft” ionization technique of electrospray ionization mass spectrometry are revisited.
Cunniff, John B., Vouros, Paul
core +1 more source
Liquid chromatography-tandem mass spectrometry - Application in the clinical laboratory [PDF]
, 2003 This review provides a concise survey of liquid chromatography tandem mass spectrometry (LCTMS) as an emerging technology in clinical chemistry. The combination of two mass spectrometers with an interposed collision cell characterizes LCTMS as an ...
Ford RE +7 more
core +1 more source
Native Mass Spectrometry and Nucleic Acid G-Quadruplex Biophysics: Advancing Hand in Hand [PDF]
Accounts of Chemical Research, 2021, 54 (19), pp.3691-3699, 2023 While studying nucleic acids to reveal the weak interactions responsible for their three-dimensional structure and for their interactions with drugs, we also contributed to the field of biomolecular mass spectrometry, both in terms of fundamental understanding and with new methodological developments.
arxiv +1 more source
Probing metal ion binding and conformational properties of the colicin E9 endonuclease by electrospray ionization time-of-flight mass spectrometry [PDF]
, 2002 Nano-electrospray ionization time-of-flight mass spectrometry (ESI-MS) was used to study the conformational consequences of metal ion binding to the colicin E9 endonuclease (E9 DNase) by taking advantage of the unique capability of ESI-MS to allow ...
HECK, ALBERT J.R. +6 more
core +3 more sources