Results 11 to 20 of about 3,438,712 (289)

Mass spectrometric analysis of pilus assembly, amyloid fibril formation, and membrane proteins in their native state [PDF]

open access: yes, 2012
Structural analysis of proteins and their complexes is crucial to understanding protein function. This thesis demonstrates the application of mass spectrometry (MS) to the study of pilus assembly on Gram-negative bacteria and amyloid formation in ...
Leney, Aneika Corrine
core   +6 more sources

Basic principle from electrospray ionization to soft ionization mass spectrometry and development of ion source [PDF]

open access: yes, 2023
Since the electrospray phenomenon was discovered, there is still an unsolved mystery about the prinple of generating charged analyte in the soft ionization phenomenon which represented by ESI.
jiehong, luo
core   +1 more source

Relative affinity constants by electrospray ionization and Fourier transform ion cyclotron resonance mass spectrometry: calmodulin binding to peptide analogs of myosin light chain kinase [PDF]

open access: yes, 2003
Synthetic RS20 peptide and a set of its point-mutated peptide analogs have been used to analyze the interactions between calmodulin (CaM) and the CaM-binding sequence of smooth-muscle myosin light chain kinase both in the presence and the absence of Ca2+.
Lafitte, Daniel   +3 more
core   +1 more source

Estudo por espectrometria de massas de soluções de hidróxi(tosilóxi)iodobenzeno: propostas para mecanismos de desproporção

open access: yesQuímica Nova, 2012
Solutions of [hydroxy(tosyloxy)iodo]benzene (HTIB or Koser's reagent) in acetonitrile were analyzed using high resolution electrospray ionization mass spectrometry (ESI-MS) and electrospray ionization tandem mass spectrometry (ESI-MS/MS) under different ...
Ramon S. Vasconcelos   +2 more
doaj   +1 more source

Applications of Tandem Mass Spectrometry (MS/MS) in Protein Analysis for Biomedical Research

open access: yesMolecules, 2022
Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry (MALDI-MS).
Anca-Narcisa Neagu   +5 more
doaj   +1 more source

Desorption Electrospray Ionization-Mass Spectrometry of Proteins [PDF]

open access: yesAnalytical Chemistry, 2007
Desorption electrospray ionization-mass spectrometry (DESI-MS) was evaluated for the detection of proteins ranging in molecular mass from 12 to 66 kDa. Proteins were uniformly deposited on a solid surface without pretreatment and analyzed with a DESI source coupled to a quadrupole ion trap mass spectrometer.
Yong-Seung, Shin   +4 more
openaire   +2 more sources

The application of mass spectrometry imaging in traditional Chinese medicine: a review

open access: yesChinese Medicine, 2022
Mass spectrometry imaging is a frontier technique which connects classical mass spectrometry with ion imaging. Various types of chemicals could be visualized in their native tissues using mass spectrometry imaging.
Lieyan Huang   +7 more
doaj   +1 more source

Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples

open access: yesJournal of Lipid Research, 2006
Cardiolipin is a prominent component of the mitochondrial inner membranes contributing to the regulation of multiple discrete mitochondrial functions. Here, we extend shotgun lipidomics to identify and quantitate cardiolipin molecular species directly ...
Xianlin Han   +4 more
doaj   +1 more source

Inter-platform assessment of performance of high-throughput desorption electrospray ionization mass spectrometry

open access: yesTalanta Open, 2021
High throughput analysis is increasingly relevant in both industry and academia, with applications reaching from enzymology and drug discovery to organic reaction optimization and diagnostics.
Nicolás M. Morato, R. Graham Cooks
doaj   +1 more source

Analysis of Oligonucleotides by Electrospray Ionization Mass Spectrometry [PDF]

open access: yesCurrent Protocols in Nucleic Acid Chemistry, 2000
AbstractBecause of the high molecular weights and thermal lability of biomolecules such as nucleic acids and protein, they can be difficult to analyze by mass spectrometry. Such analyses require a “soft” ionization method that is capable of generating intact molecular ions.
Polo, Lenore M., Limbach, Patrick A.
openaire   +3 more sources

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