Results 31 to 40 of about 3,438,712 (289)

Electrospray Ionization Mass Spectrometry: A Technique to Access the Information beyond the Molecular Weight of the Analyte

International Journal of Analytical Chemistry, 2012
The Electrospray Ionization (ESI) is a soft ionization technique extensively used for production of gas phase ions (without fragmentation) of thermally labile large supramolecules.
Shibdas Banerjee, Shyamalava Mazumdar
doaj   +1 more source

Eletroforese capilar acoplada à espectrometria de massas (CE-MS): vinte anos de desenvolvimento Capillary electrophoresis coupled to mass spectrometry (CE-MS): twenty years of development

Química Nova, 2008
CE-MS has been increasingly used for analysis of a vast array of compounds. This article reviews the different electrophoretic modes, interfaces and mass analyzers that are commonly used in the CE-MS coupling, as well as the technique advantages and ...
Nilson Antonio Assunção, Etelvino José Henriques Bechara, Ana Valéria Colnaghi Simionato, Marina Franco Maggi Tavares, Emanuel Carrilho   +4 more
doaj   +1 more source

Synchronized dual-polarity electrospray ionization mass spectrometry [PDF]

Journal of the American Society for Mass Spectrometry, 2009
This work describes the synchronized dual-polarity (DP) electrospray ionization (ESI) method and demonstrates the first DP ESI mass spectra obtained using two mass spectrometers. Stable double Taylor cones were produced by applying two counter electric voltages with opposite polarities to one electrosprayer.
Chen, Han-Kwang, Chang, Chia-Kai, Wu, Chih-Che, Huang, Ming-Chia, Wang, Yi-Sheng   +4 more
openaire   +2 more sources

Outbreak of gastroenteritis caused by Yersinia pestis in Afghanistan. [PDF]

, 2010
Plague, which is most often caused by the bite of Yersinia pestis-infected fleas, is a rapidly progressing, serious disease that can be fatal without prompt antibiotic treatment.
Mustafa, L, Noormal, B, Leslie, T, Kakar, R, Whitehouse, CA, Ziar, N, Omar, F, Yingst, S, Mofleh, J, Ayazi, E, Rossi, C, Hami, AS, Kakar, F, Baldwin, C, E. AYAZI, L. MUSTAFA, S. YINGST, F. OMAR, C. A. WHITEHOUSE, T. LESLIE, J. MOFLEH, F. KAKAR, C. ROSSI, A. S. HAMI, C. BALDWIN, N. ZIAR, B. NOORMAL, R. KAKAR   +27 more
core   +1 more source

Comparison of Plasma Ionization- and Secondary Electrospray Ionization- High-resolution Mass Spectrometry for Real-time Breath Analysis

CHIMIA, 2022
Real-time breath analysis by high-resolution mass spectrometry (HRMS) is a promising method to noninvasively retrieve relevant biochemical information.
Jiafa Zeng, Alexandra Christen, Kapil Dev Singh, Urs Frey, Pablo Sinues   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A targeted mass spectrometric analysis of phosphatidylinositol phosphate species

Journal of Lipid Research, 2005
The development of a new mass spectrometric lipid profiling methodology permits the identification of cellular phosphatidylinositol monophosphate/phosphatidylinositol bisphosphate/phosphatidylinositol trisphosphate (PIP/PIP2/PIP3) species that includes ...
Stephen B. Milne, Pavlina T. Ivanova, Dianne DeCamp, Robert C. Hsueh, H. Alex Brown   +4 more
doaj   +1 more source

Nanobubbles in Electrospray Ionization Mass Spectrometry

Analytical Chemistry
Nanobubbles (NBs) are very small gas-filled cavities in solvents, and when their sizes reach diameters around 200 nm, they remain in solution for extended periods of time, featuring special chemical and physical properties. Here, we investigate the application of NBs in electrospray ionization.
George Joseph, Bincy Binny, Andre R Venter   +2 more
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Assignment of polymorphic species of insulin analogues in ion mobility mass spectroscopy

Data in Brief, 2017
Electrospray ionization – ion mobility spectrometry – mass spectrometry (ESI–IMS–MS) allows the identification of protein polymorphic distribution of protein conformers and oligomers.
Maely P. Fávero-Retto, Luiz Henrique Guerreiro, Cássio M. Pessanha, Leonardo C. Palmieri, Luís Maurício T.R. Lima   +4 more
doaj   +1 more source