Analysis of Oligonucleotides by Electrospray Ionization Mass Spectrometry [PDF]
AbstractBecause of the high molecular weights and thermal lability of biomolecules such as nucleic acids and protein, they can be difficult to analyze by mass spectrometry. Such analyses require a “soft” ionization method that is capable of generating intact molecular ions.
Polo, Lenore M., Limbach, Patrick A.
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The application of mass spectrometry imaging in traditional Chinese medicine: a review
Mass spectrometry imaging is a frontier technique which connects classical mass spectrometry with ion imaging. Various types of chemicals could be visualized in their native tissues using mass spectrometry imaging.
Lieyan Huang +7 more
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Analysis of Methoxymethylbenzoguanamine Resins Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and Electrospray Ionization Mass Spectrometry [PDF]
Methoxymethylbenzoguanamine resins were analyzed by matrix-assisted laser desorption/ionization timeof-flight mass spectrometry (MALDI-TOF-MS) and electrospray ionization mass spectrometry (ESI-MS).
Fujiwara, Hiroki +13 more
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Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples
Cardiolipin is a prominent component of the mitochondrial inner membranes contributing to the regulation of multiple discrete mitochondrial functions. Here, we extend shotgun lipidomics to identify and quantitate cardiolipin molecular species directly ...
Xianlin Han +4 more
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High throughput analysis is increasingly relevant in both industry and academia, with applications reaching from enzymology and drug discovery to organic reaction optimization and diagnostics.
Nicolás M. Morato, R. Graham Cooks
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This short review aims to summarize the current developments and applications of mass spectrometry-based methods for in situ profiling and imaging of plants with minimal or no sample pre-treatment or manipulation.
Aleš eSvatoš, Benjamin eBartels
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Methods for structural characterisation of Quillaja saponins by electrospray ionisation ion trap multiple-stage mass spectrometry [PDF]
This thesis describes methods for structural classification of Quillaja saponins based on high performance liquid chromatography hyphenated electrospray ionisation ion trap multiple-stage mass spectrometry, in combination with multivariate analysis ...
Bankefors, Johan
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Ionization and transmission efficiency in an electrospray ionization—mass spectrometry interface [PDF]
The ionization and transmission efficiencies of an electrospray ionization (ESI) interface were investigated to advance the understanding of how these factors affect mass spectrometry (MS) sensitivity. In addition, the effects of the ES emitter distance to the inlet, solution flow rate, and inlet temperature were characterized.
Page, Jason S. +3 more
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Single-Cell Analysis and Its Applications by Surface Desorption Ambient Mass Spectrometry
As the fundamental units of the structure and function of living organisms, cells perform the core functions of life activities. With the deepening research in life sciences, the importance of studies on cellular heterogeneity has become increasingly ...
Dan LIN +5 more
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Background Mass spectrometry imaging (MSI) data often consist of tens of thousands of mass spectra collected from a sample surface. During the time necessary to perform a single acquisition, it is likely that uncontrollable factors alter the validity of ...
Paolo Inglese +4 more
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