Results 21 to 30 of about 105,942 (260)

Single-Cell Analysis and Its Applications by Surface Desorption Ambient Mass Spectrometry

Zhipu Xuebao
As the fundamental units of the structure and function of living organisms, cells perform the core functions of life activities. With the deepening research in life sciences, the importance of studies on cellular heterogeneity has become increasingly ...
Dan LIN, Xi-yang GE, Xin-er XING, Yong HE, Jin OUYANG, Na NA   +5 more
doaj   +1 more source

Electrospray Ionization Mass Spectrometry: A Technique to Access the Information beyond the Molecular Weight of the Analyte

International Journal of Analytical Chemistry, 2012
The Electrospray Ionization (ESI) is a soft ionization technique extensively used for production of gas phase ions (without fragmentation) of thermally labile large supramolecules.
Shibdas Banerjee, Shyamalava Mazumdar
doaj   +1 more source

Detection of Plasmodium vivax in a child returning from India by use of broad-range PCR and electrospray ionization mass spectrometry

Emerging Microbes and Infections, 2012
Plasmodium vivax is a common cause of imported malaria in the USA, second only to P. falciparum. We present a case of P. vivax malaria in a child returning from India. P.
Megan A Rounds, Christopher D Crowder, Charles W Stratton, David J Ecker, Mark W Eshoo, Yi-Wei Tang   +5 more
doaj   +1 more source

Eletroforese capilar acoplada à espectrometria de massas (CE-MS): vinte anos de desenvolvimento Capillary electrophoresis coupled to mass spectrometry (CE-MS): twenty years of development

Química Nova, 2008
CE-MS has been increasingly used for analysis of a vast array of compounds. This article reviews the different electrophoretic modes, interfaces and mass analyzers that are commonly used in the CE-MS coupling, as well as the technique advantages and ...
Nilson Antonio Assunção, Etelvino José Henriques Bechara, Ana Valéria Colnaghi Simionato, Marina Franco Maggi Tavares, Emanuel Carrilho   +4 more
doaj   +1 more source

Comparison of Plasma Ionization- and Secondary Electrospray Ionization- High-resolution Mass Spectrometry for Real-time Breath Analysis

CHIMIA, 2022
Real-time breath analysis by high-resolution mass spectrometry (HRMS) is a promising method to noninvasively retrieve relevant biochemical information.
Jiafa Zeng, Alexandra Christen, Kapil Dev Singh, Urs Frey, Pablo Sinues   +4 more
doaj   +1 more source

Synchronized dual-polarity electrospray ionization mass spectrometry [PDF]

Journal of the American Society for Mass Spectrometry, 2009
This work describes the synchronized dual-polarity (DP) electrospray ionization (ESI) method and demonstrates the first DP ESI mass spectra obtained using two mass spectrometers. Stable double Taylor cones were produced by applying two counter electric voltages with opposite polarities to one electrosprayer.
Chen, Han-Kwang, Chang, Chia-Kai, Wu, Chih-Che, Huang, Ming-Chia, Wang, Yi-Sheng   +4 more
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A targeted mass spectrometric analysis of phosphatidylinositol phosphate species

Journal of Lipid Research, 2005
The development of a new mass spectrometric lipid profiling methodology permits the identification of cellular phosphatidylinositol monophosphate/phosphatidylinositol bisphosphate/phosphatidylinositol trisphosphate (PIP/PIP2/PIP3) species that includes ...
Stephen B. Milne, Pavlina T. Ivanova, Dianne DeCamp, Robert C. Hsueh, H. Alex Brown   +4 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Assignment of polymorphic species of insulin analogues in ion mobility mass spectroscopy

Data in Brief, 2017
Electrospray ionization – ion mobility spectrometry – mass spectrometry (ESI–IMS–MS) allows the identification of protein polymorphic distribution of protein conformers and oligomers.
Maely P. Fávero-Retto, Luiz Henrique Guerreiro, Cássio M. Pessanha, Leonardo C. Palmieri, Luís Maurício T.R. Lima   +4 more
doaj   +1 more source