Mechanistic analysis of an asymmetric palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones. [PDF]
An asymmetric palladium-catalyzed conjugate addition reaction of arylboronic acids to enone substrates was investigated mechanistically. Desorption electrospray ionization coupled to mass spectrometry was used to identify intermediates of the catalytic ...
Boeser, Cornelia L +5 more
core +3 more sources
Co-populated Conformational Ensembles of β(2)-Microglobulin Uncovered Quantitatively by Electrospray Ionization Mass Spectrometry [PDF]
Ordered assembly of monomeric human β(2)-microglobulin (β(2)m) into amyloid fibrils is associated with the disorder hemodialysis-related amyloidosis. Previously, we have shown that under acidic conditions (pH
Bjorkman +46 more
core +1 more source
Exploring the Phytochemical Landscape of the Early-Diverging Flowering Plant Amborella trichopoda Baill. [PDF]
Although the evolutionary significance of the early-diverging flowering plant Amborella (Amborella trichopoda Baill.) is widely recognized, its metabolic landscape, particularly specialized metabolites, is currently underexplored.
Chang, Lijing +3 more
core +1 more source
The composition of narrow distribution poly ethylene oxide-propylene oxide copolymer (Mw ~ 8700 Da) was studied using matrix assisted laser desorption ionization (MALDI) mass spectrometry.
Houshia, Orwa Jaber, Wilkins, Charles
core +1 more source
Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level. [PDF]
‘A picture is worth a thousand words’ is an idiom from the English language (‘borrowed’ from on old Chinese proverb) that conveys the notion that a complex idea can be succinctly and fully described by a single image. Never has this expression been truer
Andrén, PE +11 more
core +3 more sources
The path of biomolecular mass spectrometry into open research
Originally designed for measuring isotope abundances and elemental masses, mass spectrometry is becoming a mainstay across life sciences. As electrospray ionization of biomolecules turns 30 and the Orbitrap mass analyzer 20, we take this opportunity to ...
doaj +1 more source
Characterization of lead-phytochelatin complexes by nano-electrospray ionization mass spectrometry
The role of phytochelatins (PCn, metal-binding oligopeptides with the general structure (γGlu - Cys)n - Gly (n = 2- 11)) in metal detoxification is assumed to be based on immobilization of metals, which prevents binding of metals to important ...
Christian eScheidegger +6 more
doaj +1 more source
Mass Spectrometry-based Methods for Phosphorylation Site Mapping of Hyperphosphorylated Proteins Applied to Net1, a Regulator of Exit from Mitosis in Yeast [PDF]
Prior to anaphase in Saccharomyces cerevisiae, Cdc14 protein phosphatase is sequestered within the nucleolus and inhibited by Net1, a component of the RENT complex in budding yeast. During anaphase the RENT complex disassembles, allowing Cdc14 to migrate
Annan, Roland S. +5 more
core +1 more source
Nanobubbles in Electrospray Ionization Mass Spectrometry
Nanobubbles (NBs) are very small gas-filled cavities in solvents, and when their sizes reach diameters around 200 nm, they remain in solution for extended periods of time, featuring special chemical and physical properties. Here, we investigate the application of NBs in electrospray ionization.
George Joseph +2 more
openaire +2 more sources
Sphingolipid activator proteins (saposins A, B, C, and D) are derived from a common precursor protein (prosaposin) and specifically activate in vivo degradation of glycolipids with short carbohydrate chains.
Keiko Tadano-Aritomi +4 more
doaj +1 more source

