Results 61 to 70 of about 6,875,638 (265)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

A critical evaluation of the current state-of-the-art in quantitative imaging mass spectrometry. [PDF]

, 2014
Mass spectrometry imaging (MSI) has evolved into a valuable tool across many fields of chemistry, biology, and medicine. However, arguably its greatest disadvantage is the difficulty in acquiring quantitative data regarding the surface concentration of ...
Ellis, Shane R., Heeren, Ron M. A., Heeren, R.M.A., Bruinen, A.L., Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics, Ellis, S.R., Bruinen, Anne L.   +7 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Performance of a corona ion source for measurement of sulfuric acid by chemical ionization mass spectrometry [PDF]

, 2010
The performance of an ion source based on corona discharge has been studied. This source is used for the detection of gaseous sulfuric acid by chemical ionization mass spectrometry (CIMS) through the reaction of NO−3 ions with H2SO4.
Rondo, L, Ehrhart, Sebastian, Curtius, Joachim, A. Kürten, Rondo, Linda, L. Rondo, Kürten, Christoph Andreas, J. Curtius, Curtius, J, S. Ehrhart, Ehrhart, S, Kürten, A   +11 more
core   +2 more sources

Real-time Detection and Tandem Mass Spectrometry of Secondary Organic Aerosols with a Quadrupole Ion Trap [PDF]

, 2020
An aerosol quadrupole ion trap mass spectrometer is reported that is sensitive, has unique capabilities to perform chemical ionization, is operated in real-time, and is able to perform tandem mass spectrometry.
Richard M., Kamens, G. Asher, Newsome, Elias P., Rosen, Gary L., Glish   +3 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Sequencing and Identification of Endogenous Neuropeptides with Matrix-Enhanced Secondary Ion Mass Spectrometry Tandem Mass Spectrometry

, 2017
Matrix-enhanced secondary ion mass spectrometry (ME-SIMS) has overcome one of the biggest disadvantages of SIMS analysis by providing the ability to detect intact biomolecules at high spatial resolution. By increasing ionization efficiency and minimizing
Nina Ogrinc Potočnik, Heeren, Ron M. A., Gregory L. Fisher, Arnoud Prop, Fisher, Gregory L., Prop, Arnoud, Potocnik, Nina Ogrinc, Ron M. A. Heeren   +7 more
core   +1 more source

Fast Mass Microscopy: Mass Spectrometry Imaging of a Gigapixel Image in 34 Minutes

, 2022
[Image: see text] Mass spectrometry imaging (MSI) maps the spatial distributions of chemicals on surfaces. MSI requires improvements in throughput and spatial resolution, and often one is compromised for the other. In microprobe-mode MSI, improvements in
Claes, Britt S. R., Heeren, Ron M. A., Claes, Britt S R, Heeren, Ron M A, Körber, Aljoscha, Anthony, Ian G. M., Keelor, Joel D., Ron M. A. Heeren, Keelor, Joel D, Britt S. R. Claes, Joel D. Keelor, Aljoscha Körber, Ian G. M. Anthony, Anthony, Ian G M   +13 more
core   +1 more source

Study on the Analysis of Uranium-in Rat Hair by Secondary Ion Mass Spectrometry

Journal of Isotopes, 2021
Hair samples, as a non-invasive biological material, it is gradually gaining attention in the fields of nuclear forensics, environmental monitoring, occupational exposure detection, and medicine due to its certain accumulation effect on human trace ...
HU Ruixuan;SHEN Yan;LI Lili;HUANG Shenghui;ZHAO Lifei;ZHAO Yonggang
doaj  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source