Results 131 to 140 of about 1,151,377 (306)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Application of Technology of Frequency-conversion Speed-regulation in Plough Mining System

open access: yesGong-kuang zidonghua, 2011
The paper introduced composition of plough mining system and application of technology of frequency-conversion speed-regulation in plough mining system.
ZHANG Shu-qi   +3 more
doaj  

Drying of the disperse material in the aero spouted bed with horizontal material moving [PDF]

open access: yes, 2013
Проведено аналіз діючих сушильних пристроїв, показані їх достоїнства й недоліки.. Розглянуто конструкцію сушильної установки з використанням киплячого прошарку з газоди-намічним транспортуванням матеріалу.Проведен анализ действующих сушильных устройств ...
Kolomiyets, R.V.
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Design of a New Type Speed Regulation Device and Research of Fuzzy PID Control

open access: yesJixie chuandong, 2019
A type of stepless speed regulation device is designed based on the differential gear train and hydro-viscous speed regulation theory, and the main parameters of the planetary gear set are determined, then transmission structure is designed in ...
Pengyun Jin, Yongzhi Liang
doaj  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Optimization technology of hydroelectric power plant unit speed control based on the constriction coefficient-based particle swarm gravitational search algorithm fusion model

open access: yesResults in Engineering
In recent years, the integration of wind power into hydropower networks has become a trend. But after wind power is connected to the grid, its unstable power will have an impact on the stability of the power grid.
Tao Song
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Review and Recent Developments of Speed Regulation Technology for Energy Conservation Based on Permanent Magnet Adjustable Speed Drive

open access: yesIEEE Access
The speed regulation technology for energy conservation of pump and fan systems occupies an important position in industrial field. The paper focuses on the rapid development and research significance of speed regulation technology for energy ...
Yibo Li   +4 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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