Results 121 to 130 of about 273,320 (297)
Advanced Science, EarlyView.The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang +23 more
wiley +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo +3 more
wiley +1 more source
Manifold limits on seed production by individual flowering plants
American Journal of Botany, EarlyView.Abstract Premise Historically, angiosperm seed production has been considered to be either pollen or resource limited. However, seed production involves more than pollen and seed resources and typically involves multiple ovules in multiple flowers. Therefore, various constraints may act simultaneously. Methods Proportional components of seed production
Lawrence D. Harder +1 more
wiley +1 more source
Selenoproteins in mammalian spermatogenesis:role of the nuclear GPx4 [PDF]
, 2011 The selenoprotein Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPx/GPx4) is an enzyme unique among the various GPxs, because it is able to use protein thiols, beside glutathione, The GPx4 gene encodes for three isoforms having different ...
Maccari, Irene
core
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman +15 more
wiley +1 more source
The Surface Proteome of Bovine Unsexed and Sexed Spermatozoa
AnimalsCurrent sperm sexing methods are costly and largely restricted to cattle, while immunological techniques targeting sex-specific membrane proteins may offer more economical alternatives.
Patrícia Pinto-Pinho +9 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.Our study demonstrated that a single bilateral intra‐testicular injection of 50% dextrose (Group A) and 20% mannitol (Group B) solutions cannot serve as chemical sterilizing agents in male rabbits. However, intra‐testicular injection of 0.9% saline (Group C) significantly reduced the seminiferous tubule quality (STQ), seminiferous tubule maturity (STM),
Mohammad‐Javad Gholizadeh +2 more
wiley +1 more source
Sperm DNA and detection of DNA fragmentations in sperm
Urology Research and Practice, 2019 The questionable effectiveness of routine sperm parameters in determining male factor infertility problems and increasing the success rates of assisted reproductive techniques have led to the investigation of more detailed sperm parameters that could ...
Niyazi Küçük
doaj +1 more source
Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood
Advanced NanoBiomed Research, EarlyView.Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus +5 more
wiley +1 more source
Fifty years of sperm cell isolations: from structural to omic studies. [PDF]
J Exp Bot, 2023 Flores-Tornero M, Becker JD.
europepmc +1 more source