The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai +15 more
wiley +1 more source
Sperm DNA Fragmentation Impairs Early Embryo Development but Is Not Predictive of Pregnancy Outcomes: Insights from 870 ICSI Cycles. [PDF]
Machałowski T +6 more
europepmc +1 more source
CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source
Total Round Cell Concentration in Semen and Its Association With Sperm DNA Fragmentation Index Among Ghanaian Males in Kumasi. [PDF]
Anokye Kumi E +6 more
europepmc +1 more source
The relationship between sperm viability and DNA fragmentation rates [PDF]
Alaina Garbens +6 more
core +1 more source
Heat Therapy: Targeting Health, Disease, and Disability
The predominance of evidence suggests heat therapy has an impact on all aspects of health and performance, but the drivers of that improvement, the extent to which they are improved, and the specific populations in which improvements manifest are far from completely understood.
Rauchelle E. Richey +5 more
wiley +1 more source
Association between serum Vitamin D levels and sperm DNA fragmentation index in varicocele patients: a retrospective cohort study. [PDF]
Cai T, Zhang R, Chen K, He J, Zhan T.
europepmc +1 more source
Obligatory brood parasitism in the Lake Tanganyika cuckoo catfish requires rapid reproductive readiness to exploit unpredictable host spawning. Our experiments showed that males are almost continuously ready to reproduce, while females ovulate about once a week, with social interactions enhancing gamete maturation in both sexes.
Holger Zimmermann +5 more
wiley +1 more source
Association of sperm DNA fragmentation with higher miscarriage rates in non-male factor infertility reproductive cycles. [PDF]
Yu H, Shi C, Zhan C, Wang C, Chen J.
europepmc +1 more source
New approach to assess sperm DNA fragmentation dynamics: Fine-tuning mathematical models [PDF]
core +1 more source

