Results 221 to 230 of about 16,246 (249)
Some of the next articles are maybe not open access.
Sperm DNA fragmentation in men with malignancy
Fertility and Sterility, 2013To determine if men with malignancy have increased sperm DNA fragmentation compared with men presenting for sperm donation.Retrospective observational study.Tertiary-level fertility center.Eighty-nine men with cancer presenting for prophylactic semen cryopreservation and 35 men presenting for sperm donation.None.Sperm DNA fragmentation index (DFI ...
McDowell, Simon +4 more
openaire +3 more sources
Sperm DNA Fragmentation and Base Oxidation
2013Sperm DNA damage has been shown to be a valuable diagnostic and prognostic biomarker for male infertility and assisted reproductive treatment (ART) outcome. It is linked to every fertility checkpoint from reduced fertilization rates, lower embryo quality and pregnancy rates to higher rates of spontaneous miscarriage and childhood diseases.
openaire +2 more sources
Sperm DNA fragmentation: awakening the sleeping genome
Biochemical Society Transactions, 2007We have recently demonstrated that mammalian spermatozoa have the ability to degrade their DNA by a mechanism that is similar to apoptosis in somatic cells. When this mechanism is activated, the DNA is first degraded into loop-sized fragments by TOP2B (topoisomerase IIB).
J A, Shaman, Y, Yamauchi, W S, Ward
openaire +2 more sources
Sperm DNA fragmentation is related to sperm morphological staining patterns
Reproductive BioMedicine Online, 2015In this prospective comparative study, sperm DNA fragmentation (sDNAfrag) was compared at each step of a sequential semen preparation, with semen parameters according to their degree of severity. At each step (fractions) of the sequential procedure, sDNAfrag was determined: fresh (Raw), after gradient centrifugation, washing, and swim-up (SU) for 70 ...
Rosália, Sá +4 more
openaire +2 more sources
Assessing Sperm DNA Fragmentation with the Sperm Chromatin Dispersion Test
2010The sperm cell has evolved to transmit a paternal haploid genome to the oocyte and form a new embryo. Therefore, it is essential that the integrity of this genome be evaluated as part of the standard semen analysis. The assessment of DNA fragmentation is consequently considered as an important parameter of sperm quality. The Sperm Chromatin Dispersion (
José Luis, Fernández +3 more
openaire +2 more sources
Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations
Andrologia, 2021Sandro C. Esteves +2 more
exaly
Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
exaly