Results 1 to 10 of about 222,504 (300)

Oxidative origin of sperm DNA fragmentation in the adult varicocele [PDF]

International Brazilian Journal of Urology, 2021
Purpose: Sperm DNA fragmentation is a major cellular mechanism underlying varicocele-related male infertility. However, the type of DNA fragmentation - whether oxidative or of another nature - remains unknown.
Jessica Timóteo Jeremias, Larissa Berloffa Belardin, Fatima Kazue Okada, Mariana P. Antoniassi, Renato Fraietta, Ricardo Pimenta Bertolla, Paula Intasqui   +6 more
doaj   +3 more sources

Editorial: Insights in DNA fragmentation [PDF]

Frontiers in Endocrinology
Jordi Ribas-Maynou
doaj   +5 more sources

DNA Fragmentation Analysis

Bio-Protocol, 2014
DNA fragmentation with length corresponding to multiple integer of approximately 180 base pairs is a distinct feature of apoptosis in animals and programmed cell death in plants.
Kei-ichiro Mishiba, Yukihiro Nagashima, Noriko Hayashi, Nozomu Koizumi   +3 more
doaj   +2 more sources

Sperm DNA Fragmentation: Causes, Effects and Relevance in IVF Outcomes

Fertility & Reproduction, 2023
Sperm DNA fragmentation, characterized by damaged or broken DNA strands within sperm cells, has been recognized as an important factor in male infertility and poor ART outcome.
David YL Chan
doaj   +2 more sources

Whether the Effect of Sperm DNA Fragmentation on the Clinical and Laboratory Outcomes Changes with the Paternal age in the intracytoplasmic sperm injection Cycles of Donor Oocytes

Gynecology Obstetrics & Reproductive Medicine, 2022
OBJECTIVE: The present study aimed to know the effect of paternal age together with Sperm DNA fragmentation on the clinical and laboratory outcomes in the donor oocyte intracytoplasmic sperm injection cycles.
Deepthi Repalle, saritha kv, Shilpa Bhandari, Jitendra Choudhary   +3 more
doaj   +1 more source

Evaluation of Sperm DNA Fragmentation Using Two Different Methods: TUNEL via Fluorescence Microscopy, and Flow Cytometry

Medicina, 2023
Background and Objectives: Sperm DNA fragmentation refers to any break in one or both of the strands of DNA in the head of a sperm. The most widely used methodologies for assessing sperm DNA fragmentation are the sperm chromatin structure assay (SCSA ...
Katerina Chatzimeletiou, Alexandra Fleva, Theodoros-Thomas Nikolopoulos, Maria Markopoulou, Glykeria Zervakakou, Kyriakos Papanikolaou, George Anifandis, Anastasia Gianakou, Grigoris Grimbizis   +8 more
doaj   +1 more source

MACS-annexin V cell sorting of semen samples with high TUNEL values decreases the concentration of cells with abnormal chromosomal content: a pilot study

Asian Journal of Andrology, 2022
We question whether, in men with an abnormal rate of sperm DNA fragmentation, the magnetic-activated cell sorting (MACS) could select spermatozoa with lower rates of DNA fragmentation as well as spermatozoa with unbalanced chromosome content ...
Sahar El Fekih, Nadia Gueganic, Corinne Tous, Habib Ben Ali, Mounir Ajina, Nathalie Douet-Guilbert, Hortense Drapier, Damien Beauvillard, Frédéric Morel, Aurore Perrin   +9 more
doaj   +1 more source

Comparison between density gradient centrifugation method, an extended version of the horizontal swim up method and the combination of both for sperm selection [PDF]

Obstetrics & Gynecology Science, 2023
Objective To compare the degree of efficiency between density gradient centrifugation (DGC) method and an extended horizontal swim-up (SU) method. Methods A total of 97 couples undergoing in vitro fertilization were enrolled in the study.
Malak Jamil, Hasnae Debbarh, Amal Kabit, Mohamed Ennaji, Loic Koumba, Ismail Kaarouch, Mohamed Zarqaoui, Wassim Rhazi Senhaji, El Mehdi Hissane, Brahim Saadani, Pierre Vanderzwalmen, Nourredine Louanjli, Rachida Cadi   +12 more
doaj   +1 more source

Impaired semen quality, an increase of sperm morphological defects and DNA fragmentation associated with environmental pollution in urban population of young men from Western Siberia, Russia.

PLoS ONE, 2021
Poor sperm morphology and an elevated DNA fragmentation level are considered to be related to spermiogenesis malfunctions as a result of genetic mutations and effects of environmental factors, including industrial pollution.
Maxim Kleshchev, Alexander Osadchuk, Ludmila Osadchuk   +2 more
doaj   +2 more sources

Associations of sperm DNA fragmentation with lifestyle factors and semen parameters of Saudi men and its impact on ICSI outcome

Reproductive Biology and Endocrinology, 2018
Background Male factor infertility is quite common as 30–50% of infertility cases are due to sperm defects. The high sperm DNA fragmentation is one of the causes of male factor infertility.
Basmah Al Omrani, Nadia Al Eisa, Murid Javed, Maher Al Ghedan, Hamoud Al Matrafi, Hamad Al Sufyan   +5 more
doaj   +1 more source