Results 81 to 90 of about 101,802 (324)
Varicocele-Associated Infertility and the Role of Oxidative Stress on Sperm DNA Fragmentation
Frontiers in Reproductive Health, 2021 Varicocele has been extensively described and studied as the most important reversible cause of male infertility. Its impact on semen parameters, pregnancy rates, and assisted reproductive outcomes have been associated with multifactorial aspects, most ...
G. Wood +4 more
semanticscholar +1 more source
Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
Advanced Science, EarlyView.In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
wiley +1 more source
Journal of Family and Reproductive HealthObjective: To determine the sperm DNA fragmentation in the semen of suspected sub-fertile men of Nepal and find its association with bacteriospermia demographic and lifestyle factors. Materials and methods: A cross-sectional study was conducted with the
Anima Shrestha +4 more
doaj +1 more source
Effect of microsurgical varicocelectomy on sperm DNA fragmentation in infertile men
Middle East Fertility Society Journal, 2011 Objectives: To examine the effect of microsurgical varicocelectomy on the sperm DNA damage in infertile men. Setting: Private clinical practice. Design: Prospective study.
Sherif Ghazi, Howida Abdelfattah
doaj +1 more source
Smoke, alcohol and drug addiction and male fertility [PDF]
, 2018 In recent decades, the decline in human fertility has become increasingly more worrying: while therapeutic interventions might help, they are vexing for the couple and often burdened with high failure rates and costs.
DE ANGELIS, Cristina Concetta +7 more
core +1 more source
The effect of sperm DNA fragmentation on intracytoplasmic sperm injection outcome
Andrologia, 2021 Our study objective was to assess the effect of various sperm DNA fragmentation levels on clinical intracytoplasmic sperm injection outcome. This retrospective study included 392 patients who underwent ICSI and performed sperm DNA fragmentation testing ...
K. Khalafalla +9 more
semanticscholar +1 more source
Amphibian sperm DNA fragmentation [PDF]
, 2016 There are extremely limited studies that have investigated DNA fragmentation in amphibians and even less information exists pertaining to DNA fragmentation in the spermatozoa. A DNA fragmentation assay applied and validated for amphibian spermatozoa would not only provide the first evidence of this phenomenon in a new major taxon, but also prove a ...
openaire +2 more sources
Reactive oxygen species and sperm DNA fragmentation [PDF]
Translational Andrology and Urology, 2017 Dr. Dada demonstrated her extensive knowledge about sperm DNA fragmentation (SDF) in her elegantly written commentary with a comprehensive discussion on issues such as genetic health of offspring, value of SDF testing in lifestyle factors, modification of SDF by oocyte, role of sperm preparation, concept of reductive stress, methodology of SDF testing,
Agarwal, Ashok +3 more
openaire +2 more sources
Advanced Science, EarlyView.We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun +5 more
wiley +1 more source
International Journal of Reproductive BioMedicine, 2021 Background: The examination of sperm parameters and sperm DNA integrity are necessary for male fertility expression. These parameters can be affected by method of sperm separation.
Zeynab Yazdanpanah +2 more
doaj +1 more source