Results 61 to 70 of about 14,205 (205)

Heat stress in spermatogenesis: a redox‐dependent decision network linking ROS, autophagy, and regulated cell death

Biological Reviews, EarlyView.
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley   +1 more source

A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse. [PDF]

, 2012
Intragenomic conflicts arise when a genetic element favours its own transmission to the detriment of others. Conflicts over sex chromosome transmission are expected to have influenced genome structure, gene regulation, and speciation.
Shantha K. Mahadevaiah (94714), Nabeel A. Affara (135531), Vaiman, Daniel, Julie Cocquet, Nabeel A Affara, Burgoyne, Paul S., Daniel Vaiman, Cocquet, Julie, Affara, Nabeel A., Julie Cocquet (135523), Mahadevaiah, Shantha K., Ellis, Peter J.I., Peter J I Ellis, Shantha K Mahadevaiah, Daniel Vaiman (83223), Paul S. Burgoyne (94717), Peter J. I. Ellis (135526), Paul S Burgoyne   +17 more
core   +1 more source

Behavioral mechanisms of mammalian sperm guidance

Asian Journal of Andrology, 2015
In mammals, sperm guidance in the oviduct appears essential for successful sperm arrival at the oocyte. Hitherto, three different potential sperm guidance mechanisms have been recognized: thermotaxis, rheotaxis, and chemotaxis, each of them using ...
Serafín Pérez Cerezales, Sergii Boryshpolets, Michael Eisenbach   +2 more
doaj   +1 more source

Linking Phospho-Gonadotropin Regulated Testicular RNA Helicase (GRTH/DDX25) to Histone Ubiquitination and Acetylation Essential for Spermatid Development During Spermiogenesis

Frontiers in Cell and Developmental Biology, 2020
GRTH/DDX25 is a testicular RNA helicase expressed in germ cells that plays a crucial role in completion of spermatogenesis. Previously, we demonstrated a missense mutation (R242H) of GRTH gene in Japanese infertile patients (5.8%) with non-obstructive ...
Raghuveer Kavarthapu, Rajakumar Anbazhagan, Ashish K. Sharma, Joseph Shiloach, Maria L. Dufau   +4 more
doaj   +1 more source

The tumor suppressor archipelago E3 ligase is required for spermatid differentiation in Drosophila testis

Scientific Reports, 2021
The human orthologue of the tumor suppressor protein FBW7 is encoded by the Drosophila archipelago (ago) gene. Ago is an F-box protein that gives substrate specificity to its SCF ubiquitin ligase complex.
Viktor Vedelek, Attila L. Kovács, Gábor Juhász, Elham Alzyoud, Rita Sinka   +4 more
doaj   +1 more source

Low‐Dose Chlorothalonil Induces Testicular Injury Through Disruption of Steroidogenic Signaling in Adult Male Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorothalonil (CHL) is a widely used organochlorine fungicide frequently detected in environmental and food matrices. Although increasing evidence indicates adverse effects in nontarget species, the mechanisms underlying CHL‐induced male reproductive toxicity remain incompletely understood.
Cristiana Livramento Oliveira Pinto, Nicoly Caixêta Gonçalves, Paula Rafaela Queiroz da Silva, Ludmila Rodrigues Pontes, Juliana Reis Machado, Virmondes Rodrigues Jr., Hugo Felix Perini, Gláucia Eloisa Munhoz de Lion Siervo   +7 more
wiley   +1 more source

Pengaruh Ekstrak Etanol Propolis terhadap Penurunan Jumlah Spermatid Mencit (Mus musculus) yang Dipapar Asap Rokok [PDF]

, 2017
ABSTRAK Mugi Tri Sutikno, G0011141, 2014. Pengaruh Ekstrak Etanol Propolis terhadap Penurunan Jumlah Spermatid Mencit (Mus Musculus) yang Dipapar Asap Rokok. Skripsi. Fakultas Kedokteran. Universitas Sebelas Maret Surakarta. Latar Belakang.
SUTIKNO, MUGI TRI
core  

Caspase Activity Is Required for Spermatid Individualization

, 2013
(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows. (B and C)
Hong Yu (6528), Ming Guo (34061), Bruce A Hay (34063), Yigong Shi (68544), Jun R Huh (70334), Stephanie Y Vernooy (70335), Nieng Yan (70336)   +6 more
core   +1 more source

Development of a procedure for isolation, identification and quality assessment of bovine spermatids and evaluation of their fertilizing ability in vitro

Frontiers in Bioengineering and Biotechnology
Intracytoplasmic spermatid injection into oocytes has limited efficiency in cattle, with no offspring generated so far, partly due to ambiguous spermatid identification.
Rolando Pasquariello, Francesca Di Filippo, Sai Kamal Nag Bonumallu, Fernanda Fagali Franchi, Ramona Pistucci, Federica Franciosi, Valentina Lodde, Alessandra Iannuzzi, Alberto Maria Luciano, Tiziana A. L. Brevini, Fulvio Gandolfi   +10 more
doaj   +1 more source

The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition

Asian Journal of Andrology, 2015
One of the most common lesions present in the spermatozoa of human infertility patients is an idiopathic failure of sperm-egg recognition. Although this unique cellular interaction can now be readily by-passed by assisted reproductive strategies such as ...
Brett Nixon, Elizabeth G Bromfield, Matthew D Dun, Kate A Redgrove, Eileen A McLaughlin, R John Aitken   +5 more
doaj   +1 more source