Results 41 to 50 of about 20,184 (239)

Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertility

Asian Journal of Andrology, 2015
The classical idea about the function of the mammalian sperm chromatin is that it serves to transmit a highly protected and transcriptionally inactive paternal genome, largely condensed by protamines, to the next generation.
Judit Castillo, Josep Maria Estanyol, Josep Lluis Ballescà, Rafael Oliva   +3 more
doaj   +1 more source

Sertoli Cell‐Derived Extracellular Vesicles Orchestrate Cadmium‐Induced Testicular Inflammation and Fibrosis

Advanced Science, EarlyView.
Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.
Jianfeng Ma, Mailin Gan, Shuang Liang, Siyu Chen, Ziling Hao, Yiting Yang, Jiawei Lu, Qihang Wu, Yuqian Shi, Lijun Sun, Jiaxin Li, Saihao Wang, Yan Wang, Xiaofeng Zhou, Lei Chen, Ye Zhao, Li Zhu, Linyuan Shen   +17 more
wiley   +1 more source

Intracytoplasmic spermatid injection and in vitro maturation: fact or fiction?

Clinics
Intracytoplasmic injection with testicular spermatozoa has become a routine treatment in fertility clinics. Spermatozoa can be recovered in half of patients with nonobstructive azoospermia.
Veerle Vloeberghs, Greta Verheyen, Herman Tournaye   +2 more
doaj   +1 more source

New insights into the regulation of cholesterol efflux from the sperm membrane

Asian Journal of Andrology, 2015
Cholesterol is an essential component of the mammalian plasma membrane because it promotes membrane stability without comprising membrane fluidity. Given this important cellular role, cholesterol levels are tightly controlled at multiple levels.
Tamara Leahy, Bart M Gadella
doaj   +1 more source

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

Animal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun, Donglei Sun, Haishen Wen, Xin Qi, Chao Li, Xiaoyan Zhang, Yun Li   +6 more
wiley   +1 more source

Chromatin condensation during Drosophila spermiogenesis and decondensation after fertilization. [PDF]

, 2005
Eine typische Eigenschaft der männlichen Keimzellen ist die Kondensation des Chromatins. Während in Säugern bekannt ist, dass in der Spermiogenese die Histone zuerst durch Transitionsproteine und dann durch Protamine ersetzt werden, ist in Drosophila ...
Jayaramaiah Raja, Sunil, Renkawitz-Pohl, Renate   +1 more
core   +1 more source

Three-dimensional reconstruction of rat sperm using volume electron microscopy

Acta Biochimica et Biophysica Sinica
Three-dimensional (3D) reconstruction serves as a crucial instrument for the analysis of biological structures. In particular, a comprehensive and accurate 3D ultrastructural examination of rat sperm is vital for understanding and diagnosing male ...
Liu Jiazheng, Lin Limei, Zhang Lina, Ma Hongtu, Chen Xi, Pang Keliang, Li Linlin, Han Hua   +7 more
doaj   +1 more source

Search and identification of spermatozoa and spermatids in the ejaculate of non-obstructive azoospermic patients

International Brazilian Journal of Urology, 2005
OBJECTIVE: To search and to identify spermatozoa and spermatids, present in the ejaculate of non-obstructive azoospermic patients. MATERIALS AND METHODS: 27 patients, aged between 18 and 48 years, with initial diagnosis compatible with non-obstructive ...
Odival Timm Jr, Agnaldo P. Cedenho, Deborah M. Spaine, Marcia H.P. Buttignol, Renato Fraietta, Valdemar Ortiz, Miguel Srougi   +6 more
doaj   +1 more source

Spermatid cyst polarization in Drosophila depends upon apkc and the CPEB family translational regulator orb2. [PDF]

PLoS Genetics, 2014
Mature Drosophila sperm are highly polarized cells--on one side is a nearly 2 mm long flagellar tail that comprises most of the cell, while on the other is the sperm head, which carries the gamete's genetic information.
Shuwa Xu, Sanjay Tyagi, Paul Schedl
doaj   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source