Results 41 to 50 of about 14,205 (205)

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source

Time-lapse imaging of Drosophila testis for monitoring actin dynamics and sperm release

STAR Protocols, 2022
Summary: Here we describe a simple step-by-step protocol for collecting high-resolution, time-lapse images of intact Drosophila testis ex vivo for a limited period using a confocal microscope, with minimum photo-toxic damage, to monitor spermatid ...
Tushna Kapoor, Pankaj Dubey, Krishanu Ray   +2 more
doaj   +1 more source

Number of spermatid-like cells at 48 h post-transfection.

, 2018
(A) Fluorescence images of TSA-treated cells. White arrows indicate spermatid-like cells. Scale bar represents 10 μm. (B) Graphic representation of spermatid-like cells at 48 h after transfection in relation of TSA concentration: “a” mean value P = 0 ...
Luca Palazzese (4634500), Marta Czernik (289953), Paola Toschi (329827), Domenico Iuso (289952), Pasqualino Loi (289972)   +4 more
core   +1 more source

The impact of hydroalcoholic extracts of Peganum harmala and Piper longum on pituitary- gonad axis hormone levels of male NMRI mice

یافته‌های نوین در علوم زیستی, 2017
Several therapeutic effects have been reported for Peganum harmala and Piper longum. These plants contain flavonoids that probably can affect reproductive endocrine system and reduce fertility.
Namdar Yousefvand, Delaram Eslimi Esfahani, Tayebeh Bahrami   +2 more
doaj  

Spermiogenesis and spermatozoa ultrastructure in five species of the Curimatidae with some considerations on spermatozoal ultrastructure in the Characiformes

Neotropical Ichthyology
Spermiogenesis in the curimatid species, Steindachnerina insculpta, Cyphocharax gillii, C. modestus, C. spilotus, and Potamorhina altamazonica, is characterized by lateral development of the flagellum, nuclear rotation, eccentric nuclear fossa formation,
Irani Quagio-Grassiotto, Maria Carolina Gameiro, Tatiana Schneider, Luiz Roberto Malabarba, Claudio Oliveira   +4 more
doaj   +1 more source

Search and identification of spermatozoa and spermatids in the ejaculate of non-obstructive azoospermic patients

International Brazilian Journal of Urology, 2005
OBJECTIVE: To search and to identify spermatozoa and spermatids, present in the ejaculate of non-obstructive azoospermic patients. MATERIALS AND METHODS: 27 patients, aged between 18 and 48 years, with initial diagnosis compatible with non-obstructive ...
Odival Timm Jr, Agnaldo P. Cedenho, Deborah M. Spaine, Marcia H.P. Buttignol, Renato Fraietta, Valdemar Ortiz, Miguel Srougi   +6 more
doaj   +1 more source

Evaluation of therapeutic effects of D‐limonene following orchiopexy in the rat model of cryptorchidism

Animal Models and Experimental Medicine, EarlyView.
D‐limonene supplementation enhances testicular recovery following orchiopexy in a rat model of bilateral cryptorchidism. Treatment with D‐limonene reduces oxidative stress (↓MDA, ↑SOD, ↑GPx, ↑TAC), downregulates pro‐apoptotic proteins (↓TNF‐α, ↓BAX, ↓Caspase‐3), and upregulates anti‐apoptotic Bcl‐2 expression.
Arman Norouzi‐Ghalehbala, Mohammadjavad Rezaei‐Varmaziar, Majid Taati, Ali Soleimanzadeh, Abbas Raisi, Farshid Davoodi, Amir Ali Shahbazfar   +6 more
wiley   +1 more source

Actin Binding Proteins, Spermatid Transport And Spermiation

, 2014
The transport of germ cells across the seminiferous epithelium is composed of a series of cellular events during the epithelial cycle essential to the completion of spermatogenesis.
Qian, Xiao-jing, Cheng, Yan Ho, Mruk, Dolores D., Han, Daishu, Lee, Will M., Lee, WWM, Cheng, CY, Mruk, DD, Cheng, Y-H, Qian, X, TANG, EIY, Cheng, C. Yan, Tang, Elizabeth I., Wong, WPE, Wong, Elissa W.P., Han, D   +15 more
core   +1 more source

Fate of microinjected spermatid mitochondria in the mouse oocyte and embryo

, 1998
Mouse round spermatids labelled with MitoTracker were microinjected into Sr2+-activated mouse oocytes. The labelled mitochondria were tracked up to the morula/blastocyst stage using fluorescence microscopy.
Yanagimachi, R., Wakayama, T., Cummins, J.M.   +2 more
core   +2 more sources

Male reproductive system in stenopodidean shrimps: Unveiling basal reproductive traits in shrimp‐like Pleocyemata (Stenopodidae and Spongicolidae)

The Anatomical Record, EarlyView.
Abstract Stenopodidea represents one of the basal lineages within Pleocyemata, yet the male reproductive system (MRS) of this group remains poorly understood, with limited information available regarding its morphology and function. This study provides the first detailed description of the MRS in four stenopodidean shrimp species from two families ...
Caio Santos Nogueira, Lucas Rezende Penido Paschoal, Fernando José Zara   +2 more
wiley   +1 more source