Are spermatid injections of any clinical value? ROSNI and ROSI revisited. Round spermatid nucleus injection and round spermatid injection [PDF]
Human Reproduction, 1998 Tiny numbers of spermatozoa can be extracted from an extensive testis biopsy and be used successfully for intracytoplasmic sperm injection (ICSI) in ∼60% of cases of non-obstructive azoospermia caused by testicular failure (e.g. maturation arrest, Sertoli cell only, cryptorchid atrophy, post-chemotherapy, or even Klinefelter's syndrome).
S J, Silber, L, Johnson
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Fraksi Heksan Dan Fraksi Metanol Ekstrak Biji Pepaya Muda Dapat Menghambat Spermatid Mencit Jantan (Mus Musculus) [PDF]
, 2008 Hexane fraction of unripe papaya seed extract contains glycosides, alkaloid and triterpenoids, which is assumed to have an anti fertility effect, so it can be used as a male contraception, although the mechanism of action is not yet clear.
Satriyasa, B. K. (Bagus)
core +2 more sources
Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?
Asian Journal of Andrology, 2015 This chapter explores the possibility that capacitation and apoptosis are linked processes joined by their common dependence on the continued generation of reactive oxygen species (ROS).
Robert J Aitken +2 more
doaj +1 more source
RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster. [PDF]
, 2019 Tandemly-repeated DNAs, or satellites, are enriched in heterochromatic regions of eukaryotic genomes and contribute to nuclear structure and function. Some satellites are transcribed, but we lack direct evidence that specific satellite RNAs are required ...
Allshire +44 more
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Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage
Asian Journal of Andrology, 2015 Evidence is increasing that the integrity of sperm DNA may also be related to implantation failure and recurrent miscarriage (RM). To investigate this, the sperm DNA fragmentation in partners of 35 women with recurrent implantation failure (RIF ...
Carol Coughlan +7 more
doaj +1 more source
Cell Reports, 2021 Summary: Membrane curvature recruits Bin-Amphiphysin-Rvs (BAR)-domain proteins and induces local F-actin assembly, which further modifies the membrane curvature and dynamics. The downstream molecular pathway in vivo is still unclear. Here, we show that a
Tushna Kapoor +3 more
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‘Artificial spermatid’-mediated genome editing†
Biology of Reproduction, 2019 Abstract For years, extensive efforts have been made to use mammalian sperm as the mediator to generate genetically modified animals; however, the strategy of sperm-mediated gene transfer (SMGT) is unable to produce stable and diversified modifications in descendants. Recently, haploid embryonic stem cells (haESCs) have been successfully
Lingbo Wang, Jinsong Li
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PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Fraksi Heksan Ekstrak Biji Pepaya Muda Dapat Menghambat Proses Spermatogenesis Mencit Jantan Lebih Besar Daripada Fraksi Metanol Ekstrak Biji Papaya Muda [PDF]
, 2008 Fraksi ekstrak heksan mengandung dua golongan zat aktif yang bersifat antifertilitas yaitu golongan steroid dan golongan triterpenoid yang diperkirakan bersifat antifertilitas, walupun mekanisme kerjanya belum jelas.
Satriyasa, B. K. (Bagus)
core
The role of Merlin in spermatogenesis [PDF]
, 2008 Background Drosophila Merlin, the homolog of the human Neurofibromatosis 2 (NF2) gene, is important for the regulation of cell proliferation and receptor endocytosis. Male flies carrying a Mer3 allele, a missense mutation (Met177→Ile) in the Merlin gene,
Omelyanchuk Leonid V +6 more
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