Results 91 to 100 of about 16,641 (207)

Reproductive Biology and Life‐History Plasticity of the Yellowfin Snapper Lutjanus xanthopinnis in the Southern South China Sea

Ecology and Evolution, Volume 16, Issue 8, August 2026.
The reproductive biology of the yellowfin snapper Lutjanus xanthopinnis, recently identified as a new species, was first examined across all seasons in the southwestern South China Sea. Spawning in both female and male L. xanthopinnis was observed over the years.
Takaomi Arai, Iy Vonne Tan, Norhayati Ahmad   +2 more
wiley   +1 more source

Serine Ameliorates Cadmium‐Induced Testicular Injury by Regulating the PGAM1/PHGDH Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Serine mitigates cadmium‐induced testicular injury in mice by inhibiting the PGAM1/PHGDH pathway, restoring ion homeostasis and glycolysis, and relieving oxidative stress, inflammation, fibrosis, and apoptosis. ABSTRACT Cadmium (Cd) is a widespread environmental contaminant that impairs male reproductive function; however, the metabolic mechanisms ...
Xueru Wang, Na Luo, Yonggang Ma, Hui Zou, Xishuai Tong, Jiaqiao Zhu, Ruilong Song, Hongyan Zhao, Zongping Liu   +8 more
wiley   +1 more source

Sperm characteristics as additional evidence of close relationship between Lebiasina and Piabucina (Characiformes: Lebiasinidae: Lebiasininae)

Neotropical Ichthyology
Spermiogenesis and spermatozoa of representatives of the genera Lebiasina and Piabucinaare described. Spermiogenesis is quite similar among all analyzed species of these genera and is identified as Type II.
Júlio César de O. Santana, André L. Netto-Ferreira, Daniela Calcagnotto, Irani Quagio-Grassiotto   +3 more
doaj   +1 more source

Nano‐Rosmarinic Acid Protects Against Chlorfenapyr‐Induced Testicular Toxicity Through Modulation of NRF2/HO‐1 and NF‐κB/NLRP3 Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Chlorfenapyr reduces testicular weight, sperm quality, and reproductive hormones. This study highlights that RA within chitosan nanoparticles (RA‐CHNPs) are superior to Rosmarinic acid in mitigating CFP‐induced testicular damage. RA within chitosan nanoparticles leads to the reduction of NF‐κB and NLRP3 expression in seminiferous tubules and activates ...
Ahmad Najem Alshammari, Ayat B. Al‐Ghafari, Huda A. Al Doghaither, Ahmed M. S. Hegazy, Ekramy M. Elmorsy, Asmaa Fady Sharif, Zahraa Khalifa Sobh   +6 more
wiley   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Application of genome tagging technology in elucidating the function of sperm-specific protein 411 (Ssp411)

Asian Journal of Andrology
The genome tagging project (GTP) plays a pivotal role in addressing a critical gap in the understanding of protein functions. Within this framework, we successfully generated a human influenza hemagglutinin-tagged sperm-specific protein 411 (HA-tagged ...
Xue-Hai Zhou, Min-Min Hua, Jia-Nan Tang, Bang-Guo Wu, Xue-Mei Wang, Chang-Gen Shi, Yang Yang, Jun Wu, Bin Wu, Bao-Li Zhang, Yi-Si Sun, Tian-Cheng Zhang, Hui-Juan Shi   +12 more
doaj   +1 more source

Elevated LncRNA LINC00966 Suppresses PDE2A to Impair Sperm Motility in Asthenozoospermia

FASEB BioAdvances, Volume 8, Issue 8, August 2026.
This study identifies LINC00966 as an upregulated lncRNA in asthenozoospermia associated with reduced sperm quality. Linc00966 suppresses Pde2a, disrupts cGMP signaling, and promotes oxidative stress, thereby impairing spermatogenic cell viability and migration.
Bingrou Guo, Junyi Ke, Hanran Mai, Ting Zhang, Zhaojin Lu, Zilin Zheng, Jieyi Luo, Yifan Zhang, Mei Yan, Shuo Yang, Yanxia Qu, Fan Jiang, Xiaoping Liu, Hao Chen, Liandong Zuo   +14 more
wiley   +1 more source

Intracytoplasmic spermatid injection and in vitro maturation: fact or fiction?

Clinics, 2013
Intracytoplasmic injection with testicular spermatozoa has become a routine treatment in fertility clinics. Spermatozoa can be recovered in half of patients with nonobstructive azoospermia.
Veerle Vloeberghs, Greta Verheyen, Herman Tournaye   +2 more
doaj  

AID‐Mediated Protein Knockdown Reveals the Requirement of NANOS2 in Prenatal Gonocytes for Establishing Functional Spermatogonial Stem Cells

Development, Growth &Differentiation, Volume 68, Issue 6, August 2026.
ABSTRACT The RNA‐binding protein NANOS2 plays a crucial role in male gonocyte development and the maintenance of spermatogonial stem cells. In the absence of the Nanos2 gene (Nanos2‐KO), germ cells fail to enter G0 arrest and initiate the male differentiation program (including DNA methylation and the piRNA pathway), ultimately undergoing apoptosis ...
Yumiko Saga, Quan Wu
wiley   +1 more source

Trim66’s paternal deficiency causes intrauterine overgrowth

Life Science Alliance
TRIM66 is a PHD-Bromo–containing protein primarily expressed in spermatids. Here, we report a paternal effect phenotype whereby homozygous Trim66 -mutant males sired progeny overweight at birth.
Monika Mielnicka, Francesco Tabaro, Rahul Sureka, Basilia Acurzio, Renata Paoletti, Ferdinando Scavizzi, Marcello Raspa, Alvaro H Crevenna, Karine Lapouge, Kim Remans, Matthieu Boulard   +10 more
doaj   +1 more source