Results 51 to 60 of about 16,641 (207)

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

open access: yesAndrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas   +6 more
wiley   +1 more source

Rapid spermatogenesis and structural analysis of the manchette in Chinese soft-shelled turtle, Pelodiscus sinensis

open access: yesAquaculture Reports
Rapid spermatogenesis is a special mode of sperm development pattern discovered in Chinese soft-shelled turtles (Pelodiscus sinensis). During the breeding season, numerous immature round spermatids are found in the seminiferous tubules of P.
Xi He   +8 more
doaj   +1 more source

Arachidonic acid triggers [Ca2+]i increases in rat round spermatids by a likely GPR activation, ERK signalling and ER/acidic compartments Ca2+ release. [PDF]

open access: yesPLoS ONE, 2017
Arachidonic acid (AA), a compound secreted by Sertoli cells (SC) in a FSH-dependent manner, is able to induce the release of Ca2+ from internal stores in round spermatids and pachytene spermatocytes. In this study, the possible site(s) of action of AA in
Joaquin Paillamanque   +7 more
doaj   +1 more source

The use of deidentified organ donor testes for research

open access: yesAndrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova   +4 more
wiley   +1 more source

Prophylactic effects of vitamin E and selenium on di(n-butyl) phthalate-induced testicular damage in prepubertal rats

open access: yesJournal of Advanced Biotechnology and Experimental Therapeutics, 2018
Di (n-butyl) phthalate (DBP), a potential endocrine disruptor, adversely affects male reproductive function via activation of oxidative stress. This study was conducted to investigate the protective effects of vitamin E (Vit E) and selenium (Se) on DBP ...
Mohammad Shah Alam; Md Nazmul Hoque
doaj   +1 more source

Transcriptomic Variation during Spermiogenesis in Mouse Germ Cells. [PDF]

open access: yesPLoS ONE, 2016
To explore variations in the transcription activity during spermiogenesis, round and elongated spermatids were collected from ICR/CD1 model mice using laser capture microdissection (LCM) and cauda epididymal sperm samples.
Haiyang Zuo   +7 more
doaj   +1 more source

Is there a future for spermatid injections? [PDF]

open access: yesHuman Reproduction, 1998
Microinjection of spermatids into oocytes has proven to be a successful assisted reproduction procedure in the animal model. In the human, low fertilization and cleavage to the 4-cell stage were reported after intracytoplasmic sperm injection (ICSI) with round spermatids.
P, Vanderzwalmen   +9 more
openaire   +2 more sources

The role of iron in normal and impaired testicular function

open access: yesAndrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer   +2 more
wiley   +1 more source

Elovl4 and Fa2h expression during rat spermatogenesis: a link to the very-long-chain PUFAs typical of germ cell sphingolipids[S]

open access: yesJournal of Lipid Research, 2018
The sphingolipids (SLs) of rodent spermatogenic cells (spermatocytes, spermatids) and spermatozoa contain nonhydroxylated and 2-hydroxylated versions of very-long-chain (C26–C32) PUFAs (n-V and h-V, respectively) not present in Sertoli cells (SCs). Here,
Florencia X. Santiago Valtierra   +7 more
doaj   +1 more source

CRISPR/Cas9‐mediated Genome‐editing Reveals 10 Testis‐enriched Genes and One Non‐testis‐enriched Gene are Dispensable for Male Fecundity in Mice

open access: yesAndrology, EarlyView.
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu   +2 more
wiley   +1 more source

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