Results 11 to 20 of about 32,786 (330)

EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice

open access: yeseLife, 2021
The male germ cells must adopt the correct morphology at each differentiation stage for proper spermatogenesis. The spermatogonia regulates its differentiation state by its own migration. The male germ cells differentiate and mature with the formation of
Yuki Osawa   +20 more
doaj   +2 more sources

Unique properties of Drosophila spermatocyte primary cilia

open access: yesBiology Open, 2013
Summary The primary cilium is an essential organelle required for animal development and adult homeostasis that is found on most animal cells. The primary cilium contains a microtubule-based axoneme cytoskeleton that typically grows from the mother ...
Maria Giovanna Riparbelli   +3 more
doaj   +2 more sources

A Caenorhabditis elegans protein with a PRDM9-like SET domain localizes to chromatin-associated foci and promotes spermatocyte gene expression, sperm production and fertility. [PDF]

open access: yesPLoS Genetics, 2018
To better understand the tissue-specific regulation of chromatin state in cell-fate determination and animal development, we defined the tissue-specific expression of all 36 C.
Christoph G Engert   +3 more
doaj   +2 more sources

Prokineticin 2 overexpression induces spermatocyte apoptosis in varicocele in rats

open access: goldAsian Journal of Andrology, 2019
Varicocele is one of the most important causes of male infertility, as this condition leads to a decline in sperm quality. It is generally believed that the presence of varicocele induces an increase in reactive oxygen species levels, leading to ...
Huiping Zhang   +8 more
openalex   +2 more sources

An optimised STAPUT method for the purification of mouse spermatocyte and spermatid populations [PDF]

open access: bronzeMolecular human reproduction, 2019
The purification of individual male germ cell populations is integral for molecular and biochemical characterisation of specific spermatogenic phases. Although a number of more contemporary techniques have been developed, velocity sedimentation using the
Jessica E. M. Dunleavy   +2 more
openalex   +2 more sources

Heat shock cognate 70 genes contribute to Drosophila spermatocyte growth progression possibly through the insulin signaling pathway

open access: yesDevelopment, Growth and Differentiation, 2021
Drosophila spermatocytes grow up to 25 times their original volume before the onset of male meiosis. Several insulin‐like peptides and their cognate receptors (InR) are essential for the cell growth process in Drosophila.
M. Azuma   +4 more
semanticscholar   +1 more source

Reactive oxygen species, not Ca2+, mediates methotrexate‐induced autophagy and apoptosis in spermatocyte cell line

open access: yesBasic & Clinical Pharmacology & Toxicology, 2020
Methotrexate (MTX) is widely used to treat cancers and systemic autoimmune diseases. However, it is severely toxic to healthy cells, especially those of the reproductive system, and therefore poses a great risk to patient fertility.
Suping Xiong   +9 more
semanticscholar   +1 more source

Silica nanoparticles induce unfolded protein reaction mediated apoptosis in spermatocyte cells.

open access: yesToxicological Research, 2020
With increasing air pollution, silica nanoparticles (SiNPs), as a main inorganic member of PM2.5, have gained increasing attention to its reproductive toxicity.
L. Ren   +11 more
semanticscholar   +1 more source

The Drosophila Citrate Lyase Is Required for Cell Division during Spermatogenesis [PDF]

open access: yes, 2020
The Drosophila melanogaster DmATPCL gene encodes for the human ATP Citrate Lyase (ACL) ortholog, a metabolic enzyme that from citrate generates glucose-derived Acetyl-CoA, which fuels central biochemical reactions such as the synthesis of fatty acids ...
Bucciarelli, Elisabetta   +8 more
core   +1 more source

Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]

open access: yes, 2010
Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H.   +4 more
core   +2 more sources

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