Abundant A-to-I RNA editing in spermatocytes may suppress transposons to compensate for piRNA downregulation in male germlines [PDF]
RNA BiologyThe germline genome serves as a crucial battleground for transposon expansion, as transposons can increase their copy numbers in offspring when activated within germ cells.
Yuange Duan, Qiuhua Xie, Ling Ma, Qi Cao
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Exploration of Novel Markers in Tan Sheep Spermatogenesis [PDF]
AnimalsIn livestock farming, the reproductive function and breeding performance of Tan sheep are crucial for enhancing farming efficiency. Despite advances in research on sheep germ cells, studies on the identification of markers for spermatogonia ...
Yuan Ma +5 more
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Alterations in chromosomal synapses and DNA repair in apoptotic spermatocytes of Mus m. domesticus
European Journal of Histochemistry, 2016 We investigated whether apoptotic spermatocytes from the mouse Mus m. domesticus presented alterations in chromosomal synapses and DNA repair. To enrich for apoptotic spermatocytes, the scrotum’s temperature was raised by partially exposing animals for ...
E. Ayarza +5 more
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p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes. [PDF]
PLoS Genetics, 2017 To protect germ cells from genomic instability, surveillance mechanisms ensure meiosis occurs properly. In mammals, spermatocytes that display recombination defects experience a so-called recombination-dependent arrest at the pachytene stage, which ...
Marina Marcet-Ortega +7 more
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ToxicsMale infertility, as a globally significant reproductive health issue, remains idiopathic in over 40% of cases. Reproductive disorders in males induced by environmental pollutants, such as di(2-ethylhexyl) phthalate (DEHP), have garnered considerable ...
Zhen Zhang +6 more
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Crossover frequencies in spermatocytes of Robertsonian homozygotes and heterozygotes of Mus musculus domesticus [PDF]
Genetics and Molecular BiologyCrossovers (COs) generate genetic diversity and proper homologous chromosome segregation during meiosis. Mus musculus domesticus, with a diploid number of 2n=40, has 19 autosomal pairs plus one sex chromosome pair all of which are telocentric chromosomes.
Eliana Ayarza +3 more
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Germline-Restricted Chromosome (GRC) in Diploid and Polyploid Spermatocytes of the Eurasian Bullfinch, <i>Pyrrhula pyrrhula</i> (Fringillidae, Passeriformes, Aves). [PDF]
Animals (Basel)Grishko E +3 more
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Cells, 2023 Studies on the gene regulation of spermatogenesis are of unusual significance for maintaining male reproduction and treating male infertility. Here, we have demonstrated, for the first time, that a loss of ZBTB40 function leads to abnormalities in the ...
Yinghong Cui +3 more
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Deletion of Hnrnpk Gene Causes Infertility in Male Mice by Disrupting Spermatogenesis
Cells, 2022 HnRNPK is a heterogeneous nuclear ribonucleoprotein (hnRNP) that has been firmly implicated in transcriptional and post-transcriptional regulation. However, the molecular mechanisms by which hnRNPK orchestrates transcriptional or post-transcriptional ...
Haixia Xu +9 more
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مجله دانشکده پزشکی اصفهان, 2020 Background: There has not been yet reports regarding the protective effect of vitamin C on spermatocytes in epileptic rats. The present study aimed to evaluate the protective role of vitamin C on numbers and structure spermatocytes in rats with ...
Rahim Golmohammadi +3 more
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