Results 101 to 110 of about 26,767 (249)

Microbial Metabolites Bridge Environmental Stress and Male Infertility Through a Gut–Immune Axis

Medicine Bulletin, EarlyView.
Yunchuan Tian, Xinyao Tang, Ying Shen
wiley   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

Synaptic defects in Hfm1^−/− spermatocytes.

, 2013
(a) Defects in SYCP1, TEX12 and SYCE1 deposition on synaptonemal complex of Hfm1−/− pachytene-like spermatocytes. Wild-type is shown for comparison. XY and X-Y represents the sex chromosomes.
Joseph L. Wilkerson (392634), Michel F. Guiraldelli (155116), Michael E. Dresser (162092), Craig Eyster (392633), Roberto J. Pezza (155142)   +4 more
core   +1 more source

Igsf11 deficiency leads to nonhomologous pericentric heterochromatin clustering in mouse primary spermatocytes.

, 2021
(A) Organization dynamic of PCH within primary spermatocytes of different Igsf11 genotypes. (B) Statistics of SYCP3-positive cells after early-pachytene with meiotic spread specimens.
Gengzhen Zhu (10066444), Chen Dong (967), Lin Li (28817), Jing He (58446), Bo Chen (32294), An Yan (505793), Kehkooi Kee (9188755), Yang Liu (4829), Xuerui Yang (30828)   +8 more
core   +1 more source

Vitamin B12-induced spermatogenesis recovery in cimetidine-treated rats: effect on the spermatogonia number and sperm concentration

Asian Journal of Andrology, 2017
The H2-receptor antagonist cimetidine is an antiulcer drug also used for the treatment of cancer due to its antiangiogenic effect. However, this drug has caused structural changes in the seminiferous tubules.
Flávia L Beltrame, Estela Sasso-Cerri
doaj   +1 more source

Sperm Mitochondrial DNA Copy Number and Nuclear DNA Methylation Across Clinical and Non‐Clinical Preconception Cohorts

Andrology, EarlyView.
ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant, Karolina Nowak, Amanda L. Paskavitz, Emily Houle, Ricardo P. Bertolla, Lidia Minguez‐Alarcon, Russ Hauser, J. Richard Pilsner   +7 more
wiley   +1 more source

Spatiotemporal Expression of ARRDC5 in Mammalian Spermatogenesis

Andrology, EarlyView.
ABSTRACT Background Spermiogenesis is the final phase of sperm development during which haploid round spermatids transform into specialized spermatozoa and occurs across distinct stages of sperm production in the seminiferous epithelium. Abnormalities in this process lead to malformations and an inability of sperm to fertilize eggs.
LeeLa D. Robinson, Jon M. Oatley
wiley   +1 more source

UV and genotoxic stress induce ATR relocalization in mouse spermatocytes [PDF]

, 2013
During meiosis, phosphorylation of H2AX is one of the earliest cellular responses to the generation of DNA double-strand breaks (DSBs) by the SPO11 topoisomerase. ATM is the kinase which mediates the formation of phosphorylated H2AX (H2AX) meiotic foci,
JANNINI, EMMANUELE ANGELO FRANCESCO, Rossi, P, Jannini, E, Dolci Iannini, S, Di Siena, S, JANNINI, EMMANUELE A., DI SIENA, SARA, Rossi, Pellegrino, Pellegrini, M., Campolo, F, CAMPOLO, FEDERICA, Pellegrini, Manuela, Pellegrini, M, DOLCI IANNINI, SUSANNA, DOLCI, SUSANNA   +14 more
core   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

A CCNA1 Missense Variant Associated With Chromatid Non‐Disjunction in Abnormal‐Headed Sperm and Male Infertility

Andrology, EarlyView.
ABSTRACT Background Macrozoospermia is a rare form of teratozoospermia characterized by tetraploids, large‐headed spermatozoa with multiple flagella, usually caused by bi‐allelic AURKC mutations. The etiology of atypical phenotypes with a lower proportion of large headed spermatozoa and single flagella however often remains unresolved.
Aurore Perrin, Frédéric Morel, Zeina Wehbe, Cynthia Frapsauce, Nadia Gueganic, Corinne Tous, Séverine Commet, Laura Dijols, Audrey Basinko, Nathalie Douet‐Guilbert, Célia Tebbakh, Zine‐Eddine Kherraf, Pierre F. Ray, Charles Coutton, Guillaume Martinez   +14 more
wiley   +1 more source