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The spermatogonial stem cell niche
Microscopy Research and Technique, 2009AbstractSpermatogonial stem cells (SSCs; As spermatogonia) and their direct descendants (Apr and Aal spermatogonia) are preferentially located in those areas of the seminiferous tubules that border on the interstitial tissue. Fewer of these cells are present in tubule areas directly bordering on another tubule.
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2012
The process of spermatogenesis is initiated and maintained by a rare population of single spermatogonial stem cells (SSCs). The SSCs are attached to the basement membrane of the seminiferous tubules and are characterized by typical morphological criteria.
Hossein Azizi +3 more
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The process of spermatogenesis is initiated and maintained by a rare population of single spermatogonial stem cells (SSCs). The SSCs are attached to the basement membrane of the seminiferous tubules and are characterized by typical morphological criteria.
Hossein Azizi +3 more
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Spermatogonial stem cells in the albino rat
American Journal of Anatomy, 1975AbstractThe existence of two classes of spermatogonial stem cells in the rat testis, i.e., reserve type A0 spermatogonia and renewing, types A1‐A4 spermatogonia, postulated by Clermont and Bustos‐Obregon (′68), was reexamined in a quantitative analysis of type A spermatogonia in both whole mounts of tubules and in radioautographed sections of testes ...
Y, Clermont, L, Hermo
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Spermatogonial stem cells: unlimited potential
Reproduction, Fertility and Development, 2008Recent reports have demonstrated that adult cells can be reprogrammed to pluripotency, but mostly with genes delivered using retroviruses. Some of the genes are cancer causing; thus, these adult-derived embryonic stem (ES)-like cells cannot be used for therapy to cure human diseases.
M, Dym +4 more
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2013
Spermatogonial stem cells (SSCs) constitute one of the most important stem cell systems in the adult body. SSCs are unipotent and respond for spermatogenesis in the male as they can only differentiate into sperms within the testicular niche. The long-term culture of SSCs without loss of their properties provides the opportunity to develop therapeutic ...
Ilya Chuykin +2 more
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Spermatogonial stem cells (SSCs) constitute one of the most important stem cell systems in the adult body. SSCs are unipotent and respond for spermatogenesis in the male as they can only differentiate into sperms within the testicular niche. The long-term culture of SSCs without loss of their properties provides the opportunity to develop therapeutic ...
Ilya Chuykin +2 more
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1993
Abstract Spermatogonial stem cells are responsible for the maintenance of spermatogenesis in the adult mammal. Knowledge of their regulation is important to understand the initiation of normal spermatogenesis, its recovery after toxic insults, and the modulation of fertility.
Marvin L Meistrich, Maria E A B van Beek
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Abstract Spermatogonial stem cells are responsible for the maintenance of spermatogenesis in the adult mammal. Knowledge of their regulation is important to understand the initiation of normal spermatogenesis, its recovery after toxic insults, and the modulation of fertility.
Marvin L Meistrich, Maria E A B van Beek
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Cryopreservation and Transplantation of Spermatogonial Stem Cells
2021Cryopreservation as a method that enables long-term storage of biological material has long been used for the conservation of valuable zebrafish genetic resources. However, currently, only spermatozoa of zebrafish can be successfully cryopreserved, while protocols for cryopreservation of eggs and embryos have not yet been fully developed ...
Zoran, Marinović +6 more
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Heterogeneity of Spermatogonial Stem Cells
2019Germ cells transfer genetic materials from one generation to the next, which ensures the continuation of the species. Spermatogenesis, the process of male germ cell production, is one of the most productive systems in adult tissues. This high productivity depends on the well-coordinated differentiation cascade in spermatogonia, occurring via their ...
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Is There a Clinical Future for Spermatogonial Stem Cells?
Current Stem Cell Research & Therapy, 2007Like every other adult stem cell in the human body, spermatogonial stem cells (SSCs) have the capacity to either renew themselves or to start the differentiation process, namely, spermatogenesis. Due to the continuation of the stem cell population in the testis, several possible options for preservation and re-establishment of the reproductive ...
Ellen, Goossens +3 more
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Spermatogonial stem‐cell renewal in the mouse
The Anatomical Record, 1971AbstractType A spermatogonia in the mouse can be separated into five successive classes on the basis of nuclear morphology and stage of the cycle in which they occur. Enumeration of all types throughout the cycle of the seminiferous epithelium reveals that the As spermatogonia are the stem cells.
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