Results 141 to 150 of about 52,673 (252)
Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging
Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka +4 more
wiley +1 more source
Exploring Taphrina deformans, the Springtime Scourge of Peach
This review integrates current knowledge on host–pathogen interactions, epidemiological processes, resistance mechanisms and peach‐resistant varieties, while critically identifying key knowledge gaps. It provides the first comprehensive, integrative description of the Taphrina deformans life cycle in relation to the annual developmental cycle of the ...
Clotilde Nigon +2 more
wiley +1 more source
Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros +6 more
wiley +1 more source
Effect of spermidine intake on skeletal muscle regeneration after chemical injury in male mice
Skeletal muscle has a high regenerative ability and maintains homeostasis by rapidly regenerating from frequent damage caused by intense exercise or trauma. In sports, skeletal muscle damage occurs frequently due to intense exercise, so practical methods
Tomohiro Iwata +4 more
doaj +1 more source
BAHD acyltransferases drive metabolic diversification in plants by coupling conserved catalytic scaffolds with regulatory flexibility, enabling stress adaptation and ecological specialisation. ABSTRACT BAHD acyltransferases constitute one of the most versatile enzyme superfamilies in plants, catalysing the acylation of alcohols, amines, polyamines, and
Muhammad Mubashar Zafar +7 more
wiley +1 more source
False positive spermidine adduct (+128) on Q60 of rUsp/His6.
On first inspection the y3 to y13 ion series, the score of 50.2 and the matched intensity of 89% gave strong support for a spermidine adduct on Q60. However, the absence of y1 and y2 ions leaves open an alternative interpretation.
Benjamin Girardo (12895310) +4 more
core +1 more source
Abstract Pheochromocytoma and paraganglioma with a succinate dehydrogenase B subunit (SDHB) pathogenic variant are associated with a significant chance for metastasis. Polyamine pathway inhibitor N1,N11‐diethylnorspermine (DENSPM) was previously shown to inhibit cell growth in progenitor cells derived from a human pheochromocytoma (hPheo1).
Abdel A. Alli +4 more
wiley +1 more source
Spermidine treatment: induction of autophagy but also apoptosis?
Machado-Joseph disease (MJD), also known as spinocerebellar ataxia type 3, is a fatal neurodegenerative disease that causes loss of balance and motor co-ordination, eventually leading to paralysis.
Maxinne Watchon +7 more
core +1 more source
Dicyclohexylamine is not an inhibitor of spermidine synthase [PDF]
K W, Batchelor, R A, Smith, N S, Watson
openaire +2 more sources

