Results 61 to 70 of about 7,530 (183)
Chromatin remodelling initiation during human spermiogenesis [PDF]
SummaryDuring the last phase of spermatogenesis, spermiogenesis, haploid round spermatids metamorphose towards spermatozoa. Extensive cytoplasmic reduction and chromatin remodelling together allow a dramatic decrease of cellular, notably nuclear volume.
Vries, M. de +3 more
openaire +5 more sources
Pharmacogenetics of follicle‐stimulating hormone action in the male
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani +7 more
wiley +1 more source
Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
wiley +1 more source
Abstract The sterile insect technique (SIT) is a highly effective biologically‐based method for the suppression of many insect pest populations. SIT efficacy could be improved by methods of male sterilization that avoid the use of irradiation that can result in diminished fitness and mating competitiveness.
Alfred M. Handler +3 more
wiley +1 more source
Spermatological characteristics of Calicotyle affinis Scott, 1911, an endoparasitic monocotylid monogenean from the cloaca of a holocephalan fish Chimaera monstrosa L, have been investigated by means of transmission electron microscopy for the first time.
Bruňanská M., Poddubnaya L. G.
doaj +1 more source
Fine structure of the gonadal tissue of the horned octopod Eledone cirrhosa (Lamarck, 1798) (Mollusca – Octopoda) during sexual maturity [PDF]
The horned octopod Eledone cirrhosa, a medium-sized species found in Arabian Gulf off Saudi Arabia, was collected monthly from the Arabian Gulf off Dammam city during January to December 2022.
N. AlQurashi, G. Ibrahim
doaj +1 more source
BOLL‐Containing Aggregates Mediate the Translational Regulation During Human Oogenesis
This work elucidates that BOLL‐containing aggregate‐mediated translational control is essential for human oogenesis. These aggregates recruit PABPC1 and FXR1 to activate the translation of U‐rich mRNAs encoding cell cycle proteins, thereby ensuring successful meiotic progression.
Ying Li +5 more
wiley +1 more source
The impact of autophagy in spermiogenesis
Autophagy is an evolutionarily conserved self-digestion process which is essential to keep basal homeostasis in a cell. During this process, degradation and recycling of many cytoplasmic components including the long-lived, unnecessary or aggregated proteins and damaged organelles is achieved through lysosomal machinery.
Nihan Ozturk +2 more
openaire +3 more sources
Ubiquitination Regulates the Morphogenesis and Function of Sperm Organelles
It is now understood that protein ubiquitination has diverse cellular functions in eukaryotes. The molecular mechanism and physiological significance of ubiquitin-mediated processes have been extensively studied in yeast, Drosophila and mammalian somatic
Nobuhiro Nakamura
doaj +1 more source
Euspermatozoon structure and euspermiogenesis in Cerithidea cingulata (Gmelin, 1791) (Caenogastropoda : Potamididae) [PDF]
The ultrastructural characteristics of euspermatogenesis and mature euspermatozoa of Cerithidea cingulata are described. Euspermatogonia possesses a large round concentric nucleus with one or two nucleoli.
Jintamas Suwanjarat, Sakol Suwaluk
doaj

