Results 71 to 80 of about 7,796 (196)

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

Critical Windows of Air Pollution Exposure During Spermatogenesis and Intrauterine Insemination Outcomes

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Male preconception health remains a critically under‐addressed area of family planning. While research suggests air pollution may harm semen quality, downstream impacts on pregnancy, particularly for more vulnerable infertility treatment populations, are understudied.
Lindsey M. Russo, J. Richard Pilsner, Timothy P. Canty, Neil J. Perkins, Pauline Mendola, Karen C. Schliep, May Shaaban, Rachael B. Hemmert, Akanksha Singh, Allison M. Ring, James A. Vanderslice, C. Matthew Peterson, Erica B. Johnstone, Kaniz Rabeya, Carrie Nobles   +14 more
wiley   +1 more source

The Therapeutic Effects of Crocus sativus L. and Its Constituents on the Improving Treatment of Azoospermia: A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Azoospermia, defined as the complete absence of sperm in the ejaculate, is a major cause of male infertility and is classified into obstructive and non‐obstructive forms. While obstructive azoospermia is primarily mechanical in origin, non‐obstructive azoospermia (NOA) is characterized by impaired spermatogenesis and is ...
Faraz Khakshour, Melika Hadad Tehran, Jamal Jalili Shahri, Farid Zeynali, Fahimeh Lavi Arab   +4 more
wiley   +1 more source

Loss of C-Terminal Coiled-Coil Domains in SDCCAG8 Impairs Centriolar Satellites and Causes Defective Sperm Flagellum Biogenesis and Male Fertility

Cells
Sperm flagellum defects are tightly associated with male infertility. Centriolar satellites are small multiprotein complexes that recruit satellite proteins to the centrosome and play an essential role in sperm flagellum biogenesis, but the precise ...
Kecheng Li, Xiaoli Zhou, Wenna Liu, Yange Wang, Zilong Zhang, Houbin Zhang, Li Jiang   +6 more
doaj   +1 more source

Ubiquitination Regulates the Morphogenesis and Function of Sperm Organelles

Cells, 2013
It is now understood that protein ubiquitination has diverse cellular functions in eukaryotes. The molecular mechanism and physiological significance of ubiquitin-mediated processes have been extensively studied in yeast, Drosophila and mammalian somatic
Nobuhiro Nakamura
doaj   +1 more source

A multiplex tissue resource for high‐resolution spatial protein profiling in the Human Protein Atlas

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Spatially resolved protein expression is essential for understanding tissue organization, cellular specialization, and protein function. The open‐access Human Protein Atlas database (www.proteinatlas.org) has generated an extensive antibody‐based tissue resource for a majority of the human protein‐coding genes using conventional ...
Borbala Katona, Rutger Schutten, Filippa Bertilsson, Feria Hikmet, Per Adelsköld, Mattias Forsberg, Kalle von Feilitzen, Loren Méar, Mathias Uhlén, Cecilia Lindskog   +9 more
wiley   +1 more source

Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice

Andrology, Volume 14, Issue 6, Page 1636-1646, September 2026.
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +2 more
wiley   +1 more source

Euspermatozoon structure and euspermiogenesis in Cerithidea cingulata (Gmelin, 1791) (Caenogastropoda : Potamididae) [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2003
The ultrastructural characteristics of euspermatogenesis and mature euspermatozoa of Cerithidea cingulata are described. Euspermatogonia possesses a large round concentric nucleus with one or two nucleoli.
Jintamas Suwanjarat, Sakol Suwaluk
doaj  

Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice

Andrology, Volume 14, Issue 6, Page 1472-1478, September 2026.
ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik, Jessica M. Snyder, Haley A. Martin, John K. Amory   +3 more
wiley   +1 more source

spermiogenesis

Citation: 'spermiogenesis' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11245 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +1 more source