Results 71 to 80 of about 10,170 (214)

Chromodomain Helicase DNA–Binding Proteins and Spermatogenesis: Current Advances

Andrology, EarlyView.
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Mingrui Zhang, Di Liu, Guoqiang Liu, Minggang Zhu, Feng Pan   +4 more
wiley   +1 more source

Transcriptomic Variation during Spermiogenesis in Mouse Germ Cells [PDF]

, 2016
To explore variations in the transcription activity during spermiogenesis, round and elongated spermatids were collected from ICR/CD1 model mice using laser capture microdissection (LCM) and cauda epididymal sperm samples.
Xiaoli Chen (102563), Dong Wang (73290), Haiyang Zuo (3343661), Junfang Zhang (434838), Liuguang Zhang (3343664), Haisheng Hao (594340), Xiaoxia Ren (229713), Xueming Zhao (400630)   +7 more
core   +1 more source

Spermatogenesis and spermiogenesis in Didymocystis wedli Ariola, 1902 (Didymozoidae, Digenea) [PDF]

, 2001
The ultrastructure of the male reproductive system of Didymocystis wedli was studied for the first time, demonstrating spermiogenesis and spermatogenesis at different cell stages. The spermatozoa morphology was compared with that of other Digenea species.
Anna Kohn, Kohn, Anna, MC Pamplona-Basilio, MFD Baptista-Farias, Basilio, M. C. Pamplona, A Kohn, M. C. Pamplona-Basilio, Maria de Fatima Diniz Baptista-Farias, Kohn, A, Farias, M. F. D. Baptista, Baptista-Farias, MFD, Pamplona-Basilio, MC   +11 more
core   +5 more sources

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice [PDF]

, 1996
Spermiogenesis is a complex process by which postmeiotic male germ cells differentiate into mature spermatozoa. This process involves remarkable structural and biochemical changes including nuclear DNA compaction and acrosome formation(1,2 ...
Kenth Henriksen, Paolo Sassone-Corsi, Denis Masquilier, Marianne Lemeur, MONACO, Lucia, Andree Dierich, Lucia Monaco, Nicholas S. Foulkes, François Nantel, Martti Parvinen, P. Sassonecorsi   +10 more
core   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source

SPERMIOGENESIS IN THE PULMONATE SNAIL, EUHADRA HICKONIS IV. EFFECT OF X-RAYS ON THE SPERMIOGENESIS [PDF]

Development, Growth and Differentiation, 1979
When animals were irradiated early in spermiogenesis, i. e., at the spherical nucleus stage (7), two or more flagella were observed to be formed in many cells at the subsequent stages. Other irradiation effects included the absence of cytoplasmic microtubules at an early stage followed by their excessive production later during formation of the ...
openaire   +2 more sources

Sperm Head–Tail Coupling Apparatus Diversity and Common Themes Among Species

Andrology, EarlyView.
ABSTRACT Background A stable connection between the sperm head (containing the nucleus and acrosome) and tail (containing the axoneme, mitochondrial sheath, and periaxonemal structures) is critical for fertility. This connection is mediated by a series of nuclear, cytoplasmic, and centriole components that make up the head–tail coupling apparatus (HTCA)
Danielle B. Buglak, Brian J. Galletta, Nasser M. Rusan   +2 more
wiley   +1 more source

Anatomical and Histological Structures of the Male Reproductive System of Chalcophora mariana (Linnaeus, 1758) (Coleoptera: Buprestidae): Light and Scanning Electron Microscopy Study

Acta Zoologica, EarlyView.
ABSTRACT This study presents the first detailed morphological analysis of the male reproductive system of Chalcophora mariana (Linnaeus, 1758) using stereo microscopy, light microscopy, and scanning electron microscopy. The male reproductive system of C.
Hicret Arslan, Selami Candan
wiley   +1 more source

Polyamines in spermiogenesis: Not now, darling [PDF]

Proceedings of the National Academy of Sciences, 2000
“Interesting processes invariably employ interesting biochemistry,” declares Marc Kirschner (1). From this statement, one may readily conclude that antizyme (AZ) deserves our attention. AZ is the central element in a feedback loop that controls cellular polyamines. AZ is interesting for a number of reasons. First, AZ production requires the exercise of
openaire   +2 more sources