Results 61 to 70 of about 71,184 (285)
Potential of Frangipani (Plumeria alba) Leaves Extract as Ultra Violet Protection
Borneo Journal of Pharmacy, 2020 Sunlight is the source of life and energy. Besides that, sunlight also creates skin challenges such as sunburn, pigmentation, wrinkles, dermatitis, aging, and skin cancer.
I Gusti Ngurah Agung Windra Wartana Putra +2 more
doaj +1 more source
Advanced Science, EarlyView.This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun +12 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang +8 more
wiley +1 more source
Photodermatoses: prevention and treatment
Медицинский совет, 2018 Increased exposure of the skin to sunlight has many negative effects: premature skin aging (photoaging), the risk of various skin cancers, the appearance of hyperpigmentation, and exacerbation of certain skin diseases.
O. I. Sidorovich, E. A. Tsyvkina
doaj +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Cumhuriyet Science JournalUltraviolet (UV) radiation from the sun can cause significant damage to human skin, leading to both acute and chronic adverse effects. While commercial sunscreens provide protection, increasing consumer concerns about synthetic ingredients have driven ...
Yakup Budak
doaj +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, EarlyView.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source
Antioxidant activity and sun screening effects of Bacterial melanin
Journal of BioScience and Biotechnology, 2020 The present work was delineated to formulate and evaluate antioxidant and photoprotective properties of melanin produced by Pseudomonas mosseliistrain STSGRDS1 against the purchased fungal melanin STSGRDM1 as standard. Initially,
Sharmila D.Srimathi +5 more
doaj
Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
Advanced Science, EarlyView.SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao +11 more
wiley +1 more source