Results 111 to 120 of about 79,551 (308)

Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform

open access: yesAdvanced Healthcare Materials, EarlyView.
A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu   +7 more
wiley   +1 more source

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

open access: yesAdvanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko   +7 more
wiley   +1 more source

An Automated Imaging Method for Quantification of Changes to the Endomembrane System in Mammalian Spheroid Models

open access: yesBio-Protocol
Three-dimensional cell models, such as spheroids, represent a more physiological arrangement in which cells can grow, allowing them to develop cell–cell interactions in all dimensions.
Margaritha Mysior, Jeremy Simpson
doaj   +1 more source

On retrieving shape information from scattering phase matrices using a distribution of spheroids

open access: yesAtti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2011
Phase matrices of spheroids are fitted to phase matrices of reference particles with identical sizes and refractive indices to test how well spheroids can be used to retrieve shape information from less symmetric target particles. It is found that shapes
T. Nousiainen, M. Kahnert, H. Lindqvist
doaj   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

open access: yesAdvanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang   +4 more
wiley   +1 more source

HDAC Inhibition Induces Transient Phenotypic Inertia in Dormant OCCC Spheroids by Derepression of Cell Cycle Genes

open access: yesCells
Multicellular cancer cell aggregates, termed spheroids, are anoikis-resistant, avascular, heterogeneous structures responsible for transcoelomic metastasis of ovarian clear cell carcinoma (OCCC).
Sylvia Cheng   +4 more
doaj   +1 more source

Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms

open access: yesAdvanced Healthcare Materials, EarlyView.
Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet   +11 more
wiley   +1 more source

3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs

open access: yes, 2019
Three-dimensional cell culture models, such as spheroids, can be used in the process of the development of new anticancer agents because they are able to closely mimic the main features of human solid tumors, namely their structural organization ...
Correia, I.J.   +4 more
core   +1 more source

Phase‐Pure and Size‐Tunable Tin Halide Perovskite Quantum Dots

open access: yesAdvanced Materials, EarlyView.
A trioctylphosphine oxide modulated protocol allows for the synthesis and study of the optical properties of a broad library of tin halide perovskite quantum dots across multiple A‐ and X‐site compositions with precise size tuning while eliminating unwanted 2D phases.
Ole F. Dressler   +7 more
wiley   +1 more source

Summary of Spheroids used for growth curves.

open access: yes, 2016
Summary of Spheroids used for growth curves.
Abul Siddiky (2614756)   +7 more
core   +1 more source

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