Results 1 to 10 of about 60,705 (304)

Size-dependent hepatic differentiation of human induced pluripotent stem cells spheroid in suspension culture

open access: yesRegenerative Therapy, 2019
Suspension culture of three-dimensional (3D) spheroid of human induced pluripotent stem cells (hiPSCs) has been known as a potential method to enhance the scalability of hepatic differentiation of hiPSCs.
Fuad Gandhi Torizal   +2 more
exaly   +3 more sources

Establishment of a Sensitized 3D Spheroid Cancer Cell Model for Enhanced Anti-Cancer Drug Discovery [PDF]

open access: yesMethods and Protocols
Three-dimensional (3D) spheroid cancer models provide enhanced physiological relevance relative to traditional monolayer cultures but often demonstrate restricted drug responsiveness due to their dense architecture, hypoxic gradients, and diminished ...
Ee Wern Tan   +4 more
doaj   +2 more sources

Spheroidal ambisonics: Spatial audio in spheroidal bases [PDF]

open access: yesJASA Express Letters, 2021
Ambisonics is an established framework to capture and reproduce spatial sound fields based on the spherical harmonics representation [Gerzon (1973). J. Audio Eng. Soc. 21(1), 2–10]. A generalization—spheroidal ambisonics—based on spheroidal wave functions is proposed for use with spheroidal microphone arrays.
Shoken, Kaneko, Ramani, Duraiswami
openaire   +2 more sources

Human brain organoids in Alzheimer’s disease [PDF]

open access: yesOrganoid, 2021
Alzheimer’s disease (AD) is a progressive neurological disorder that typically involves neuronal damage leading to the deterioration of cognitive and essential body functions in aging brains.
You Jung Kang, Hansang Cho
doaj   +1 more source

COORDINATE TRANSFORMATION FROM KARBALA 1979 AND WORLD GEODETIC SYSTEM 1984 TO IRAQI GEOSPATIAL REFERENCE SYSTEM [PDF]

open access: yesJournal of Engineering and Sustainable Development, 2022
Nowadays, the transformation between coordinate systems is the major interested problems especially in Iraq. There are many coordinate systems used to produce maps and documentations due to different datums and spheroids.
Ruba Y. Hussain
doaj   +1 more source

Gravity-Based Flow Efficient Perfusion Culture System for Spheroids Mimicking Liver Inflammation

open access: yesBiomedicines, 2021
The spheroid culture system provides an efficient method to emulate organ-specific pathophysiology, overcoming the traditional two-dimensional (2D) cell culture limitations.
Young-Su Kim   +5 more
doaj   +1 more source

O2-sensitive microcavity arrays: A new platform for oxygen measurements in 3D cell cultures

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Oxygen concentration plays a crucial role in (3D) cell culture. However, the oxygen content in vitro is usually not comparable to the in vivo situation, which is partly due to the fact that most experiments are performed under ambient atmosphere ...
Christoph Grün   +3 more
doaj   +1 more source

High-Efficiency Generation, Drug and Radiosensitivity Test of Multicellular Tumor Spheroids by a Novel Microdevice

open access: yesChemosensors, 2022
Compared with traditional two-dimensional culture, a three-dimensional (3D) culture platform can not only provide more reliable prediction results, but also provide a simple, inexpensive and less time-consuming method compared with animal models.
Siwei Ding   +5 more
doaj   +1 more source

Uniform Tumor Spheroids on Surface-Optimized Microfluidic Biochips for Reproducible Drug Screening and Personalized Medicine

open access: yesMicromachines, 2022
Spheroids are recognized for resembling the important characteristics of natural tumors in cancer research. However, the lack of controllability of the spheroid size, form, and density in conventional spheroid culture methods reduces the reproducibility ...
Neda Azizipour   +5 more
doaj   +1 more source

Current Research Trends in the Application of In Vitro Three-Dimensional Models of Liver Cells

open access: yesPharmaceutics, 2022
The liver produces and stores various nutrients that are necessary for the body and serves as a chemical plant, metabolizing carbohydrates, fats, hormones, vitamins, and minerals.
Chawon Yun, Sou Hyun Kim, Young-Suk Jung
doaj   +1 more source

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