Results 1 to 10 of about 67,710 (307)
Human brain organoids in Alzheimer’s disease [PDF]
Organoid, 2021 Alzheimer’s disease (AD) is a progressive neurological disorder that typically involves neuronal damage leading to the deterioration of cognitive and essential body functions in aging brains.
You Jung Kang, Hansang Cho
doaj +1 more source
COORDINATE TRANSFORMATION FROM KARBALA 1979 AND WORLD GEODETIC SYSTEM 1984 TO IRAQI GEOSPATIAL REFERENCE SYSTEM [PDF]
Journal of Engineering and Sustainable Development, 2022 Nowadays, the transformation between coordinate systems is the major interested problems especially in Iraq. There are many coordinate systems used to produce maps and documentations due to different datums and spheroids.
Ruba Y. Hussain
doaj +1 more source
Gravity-Based Flow Efficient Perfusion Culture System for Spheroids Mimicking Liver Inflammation
Biomedicines, 2021 The spheroid culture system provides an efficient method to emulate organ-specific pathophysiology, overcoming the traditional two-dimensional (2D) cell culture limitations.
Young-Su Kim +5 more
doaj +1 more source
O2-sensitive microcavity arrays: A new platform for oxygen measurements in 3D cell cultures
Frontiers in Bioengineering and Biotechnology, 2023 Oxygen concentration plays a crucial role in (3D) cell culture. However, the oxygen content in vitro is usually not comparable to the in vivo situation, which is partly due to the fact that most experiments are performed under ambient atmosphere ...
Christoph Grün +3 more
doaj +1 more source
Chemosensors, 2022 Compared with traditional two-dimensional culture, a three-dimensional (3D) culture platform can not only provide more reliable prediction results, but also provide a simple, inexpensive and less time-consuming method compared with animal models.
Siwei Ding +5 more
doaj +1 more source
Micromachines, 2022 Spheroids are recognized for resembling the important characteristics of natural tumors in cancer research. However, the lack of controllability of the spheroid size, form, and density in conventional spheroid culture methods reduces the reproducibility ...
Neda Azizipour +5 more
doaj +1 more source
Current Research Trends in the Application of In Vitro Three-Dimensional Models of Liver Cells
Pharmaceutics, 2022 The liver produces and stores various nutrients that are necessary for the body and serves as a chemical plant, metabolizing carbohydrates, fats, hormones, vitamins, and minerals.
Chawon Yun, Sou Hyun Kim, Young-Suk Jung
doaj +1 more source
Regenerative Therapy, 2019 Suspension culture of three-dimensional (3D) spheroid of human induced pluripotent stem cells (hiPSCs) has been known as a potential method to enhance the scalability of hepatic differentiation of hiPSCs.
Fuad Gandhi Torizal +3 more
doaj +1 more source
Current Issues in Molecular Biology, 2022 The expression of pluripotency factors, and their associations with clinicopathological parameters and drug response have been described in various cancers, including gastric cancer.
Han Thi Ngoc To +4 more
doaj +1 more source
Inventions and Innovations in Preclinical Platforms for Cancer Research
Inventions, 2018 Three-dimensional (3D) cell culture systems can be regarded as suitable platforms to bridge the huge gap between animal studies and two-dimensional (2D) monolayer cell culture to study chronic diseases such as cancer.
Khashayar Moshksayan +2 more
doaj +1 more source