Results 31 to 40 of about 67,710 (307)
Engineering three-dimensional bone macro-tissues by guided fusion of cell spheroids
IntroductionBioassembly techniques for the application of scaffold-free tissue engineering approaches have evolved in recent years toward producing larger tissue equivalents that structurally and functionally mimic native tissues.
Vinothini Prabhakaran +8 more
doaj +1 more source
Blood capillaries deliver oxygen and nutrients to surrounding micro-regions of tissue and carry away metabolic waste. In normal tissue, capillaries are close enough to keep all the cells viable.
Miklόs Gratzl (6713588) +1 more
core +2 more sources
Blood capillaries deliver oxygen and nutrients to surrounding micro-regions of tissue and carry away metabolic waste. In normal tissue, capillaries are close enough to keep all the cells viable.
Miklόs Gratzl (6713588) +1 more
core +2 more sources
Evaluation of Nanoparticle Penetration in the Tumor Spheroid Using Two-Photon Microscopy
Mesoporous silica nanoparticles (MSNs) have emerged as a prominent nanomedicine platform, especially for tumor-related nanocarrier systems. However, there is increasing concern about the ability of nanoparticles (NPs) to penetrate solid tumors, resulting
Feby Wijaya Pratiwi +6 more
doaj +1 more source
Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypes
Fundamental questions about patient heterogeneity and human-specific pathophysiology currently obstruct progress towards a therapy for traumatic brain injury (TBI). Human in vitro models have the potential to address these questions.
Aaron R. Shoemaker +9 more
doaj +1 more source
Mesenchymal stem cells (MSCs) reside quiescently within a specialised ‘niche’ environment in the bone marrow. However, following appropriate signalling cues, MSCs mobilise and migrate out from the niche, typically toward either sites of injury (a ...
Jake Casson +4 more
doaj +1 more source
Collagen Partition in Polymeric Aqueous Two-Phase Systems for Tissue Engineering
Aqueous two-phase systems (ATPS) of polyethylene glycol (PEG) and dextran (DEX) are commonly used to partition proteins. Protein partition in ATPS is a complex phenomenon and depends on factors including molecular weight of polymers, and electrochemical ...
Sunil Singh, Hossein Tavana
doaj +1 more source
Spheroid-3D and Monolayer-2D Intestinal Electrochemical Biosensor for Toxicity/Viability Testing: Applications in Drug Screening, Food Safety, and Environmental Pollutant Analysis [PDF]
The rise of three-dimensional cell culture systems that provide in vivo-like environments for pharmaco-toxicological models has prompted the need for simple and robust viability assays suitable for complex cell architectural structures.
Flampouri, Evangelia +7 more
core +1 more source
IntroductionSpheroids are promising building blocks for scaffold-free bone tissue engineering. Their rapid vascularization is of major importance to guarantee their survival after transplantation.
Selina Wrublewsky +9 more
doaj +1 more source

