Results 31 to 40 of about 67,710 (307)

Engineering three-dimensional bone macro-tissues by guided fusion of cell spheroids

open access: yesFrontiers in Endocrinology, 2023
IntroductionBioassembly techniques for the application of scaffold-free tissue engineering approaches have evolved in recent years toward producing larger tissue equivalents that structurally and functionally mimic native tissues.
Vinothini Prabhakaran   +8 more
doaj   +1 more source

Fig 4 O2 maps revised technical submission.pptx from Electrochemical mapping of oxygenation in the three-dimensional multicellular tumour hemi-spheroid

open access: yes, 2019
Blood capillaries deliver oxygen and nutrients to surrounding micro-regions of tissue and carry away metabolic waste. In normal tissue, capillaries are close enough to keep all the cells viable.
Miklόs Gratzl (6713588)   +1 more
core   +2 more sources

Fig 2 electrode array revised technical submission.pptx from Electrochemical mapping of oxygenation in the three-dimensional multicellular tumour hemi-spheroid

open access: yes, 2019
Blood capillaries deliver oxygen and nutrients to surrounding micro-regions of tissue and carry away metabolic waste. In normal tissue, capillaries are close enough to keep all the cells viable.
Miklόs Gratzl (6713588)   +1 more
core   +2 more sources

Evaluation of Nanoparticle Penetration in the Tumor Spheroid Using Two-Photon Microscopy

open access: yesBiomedicines, 2020
Mesoporous silica nanoparticles (MSNs) have emerged as a prominent nanomedicine platform, especially for tumor-related nanocarrier systems. However, there is increasing concern about the ability of nanoparticles (NPs) to penetrate solid tumors, resulting
Feby Wijaya Pratiwi   +6 more
doaj   +1 more source

Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypes

open access: yesDisease Models & Mechanisms, 2021
Fundamental questions about patient heterogeneity and human-specific pathophysiology currently obstruct progress towards a therapy for traumatic brain injury (TBI). Human in vitro models have the potential to address these questions.
Aaron R. Shoemaker   +9 more
doaj   +1 more source

Interleukin 6 Plays a Role in the Migration of Magnetically Levitated Mesenchymal Stem Cells Spheroids

open access: yesApplied Sciences, 2018
Mesenchymal stem cells (MSCs) reside quiescently within a specialised ‘niche’ environment in the bone marrow. However, following appropriate signalling cues, MSCs mobilise and migrate out from the niche, typically toward either sites of injury (a ...
Jake Casson   +4 more
doaj   +1 more source

Collagen Partition in Polymeric Aqueous Two-Phase Systems for Tissue Engineering

open access: yesFrontiers in Chemistry, 2018
Aqueous two-phase systems (ATPS) of polyethylene glycol (PEG) and dextran (DEX) are commonly used to partition proteins. Protein partition in ATPS is a complex phenomenon and depends on factors including molecular weight of polymers, and electrochemical ...
Sunil Singh, Hossein Tavana
doaj   +1 more source

Spheroid-3D and Monolayer-2D Intestinal Electrochemical Biosensor for Toxicity/Viability Testing: Applications in Drug Screening, Food Safety, and Environmental Pollutant Analysis [PDF]

open access: yes, 2019
The rise of three-dimensional cell culture systems that provide in vivo-like environments for pharmaco-toxicological models has prompted the need for simple and robust viability assays suitable for complex cell architectural structures.
Flampouri, Evangelia   +7 more
core   +1 more source

Biofabrication of prevascularized spheroids for bone tissue engineering by fusion of microvascular fragments with osteoblasts

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionSpheroids are promising building blocks for scaffold-free bone tissue engineering. Their rapid vascularization is of major importance to guarantee their survival after transplantation.
Selina Wrublewsky   +9 more
doaj   +1 more source

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