Results 11 to 20 of about 60,705 (304)

SpheroScan: A User-Friendly Deep Learning Tool for Spheroid Image Analysis. [PDF]

open access: yes, 2023
BACKGROUND In recent years, three-dimensional (3D) spheroid models have become increasingly popular in scientific research as they provide a more physiologically relevant microenvironment that mimics in vivo conditions.
Hashemi Gheinani, Ali   +9 more
core   +1 more source

SpheroScan: a user-friendly deep learning tool for spheroid image analysis. [PDF]

open access: yes, 2022
BACKGROUND In recent years, 3-dimensional (3D) spheroid models have become increasingly popular in scientific research as they provide a more physiologically relevant microenvironment that mimics in vivo conditions.
Hashemi Gheinani, Ali   +9 more
core   +1 more source

Modulation of Spheroid Forming Capacity and TRAIL Sensitivity by KLF4 and Nanog in Gastric Cancer Cells

open access: yesCurrent Issues in Molecular Biology, 2022
The expression of pluripotency factors, and their associations with clinicopathological parameters and drug response have been described in various cancers, including gastric cancer.
Han Thi Ngoc To   +4 more
doaj   +1 more source

Intercellular Communication in Spheroids [PDF]

open access: yes, 1984
This chapter has shown that the response of spheroid cells to gap junctional communication may lead to certain metabolic and cell physiological changes. It has also become apparent that the functions of the gap junctions are very complex. They may, for example, be related to the fundamental effects of cAMP and/or Ca 2+.
Dertinger, Hermann, Hülser, Dieter F.
openaire   +4 more sources

Spheroidal Model of SKBR3 and U87MG Cancer Cells for Live Imaging of Caspase-3 during Apoptosis Induced by Singlet Oxygen in Photodynamic Therapy

open access: yesBiomedicines, 2022
Aspects related to the response of cells to photodynamic therapy (PDT) have been well studied in cell cultures, which often grow in monolayers. In this work, we propose a spheroidal model of U87MG and SKBR3 cells designed to mimic superficial tumor ...
Viktória Pevná   +7 more
doaj   +1 more source

Inventions and Innovations in Preclinical Platforms for Cancer Research

open access: yesInventions, 2018
Three-dimensional (3D) cell culture systems can be regarded as suitable platforms to bridge the huge gap between animal studies and two-dimensional (2D) monolayer cell culture to study chronic diseases such as cancer.
Khashayar Moshksayan   +2 more
doaj   +1 more source

mansucript files zipped.zip from Electrochemical mapping of oxygenation in the three-dimensional multicellular tumour hemi-spheroid

open access: yes, 2019
Blood capillaries deliver oxygen and nutrients to surrounding micro-regions of tissue and carry away metabolic waste. In normal tissue, capillaries are close enough to keep all the cells viable.
Miklόs Gratzl (6713588)   +1 more
core   +2 more sources

High-throughput three-dimensional spheroid tumor model using a novel stamp-like tool

open access: yesJournal of Tissue Engineering, 2019
Spheroid culture is a widely used three-dimensional culture technology that simulates the three-dimensional structure of tumors in vivo and has been considered a good model for tumor research.
Wei Liao   +12 more
doaj   +1 more source

Role of cellulose family in fibril organization of collagen for forming 3D cancer spheroids: In vitro and in silico approach [PDF]

open access: yesBioImpacts, 2021
Introduction: Cell aggregation of three-dimensional (3D) culture systems (the so-called spheroids) are designed as in vitro platform to represent more accurately the in vivo environment for drug discovery by using semi-solid media.
Elaheh Dalir Abdolahinia   +5 more
doaj   +1 more source

Spheroidal Functions [PDF]

open access: yesProceedings of the National Academy of Sciences, 1935
Verf. geht aus von der Differentialgleichung für die rotationssymmetrischen Laméschen Wellenfunktionen in ihrer algebraischen Form, wie sie durch \textit{R. Maclaurin} aufgestellt wurde [Erg. Math. 1, H. 3, 69 (1934)]. Er löst diese Differentialgleichung mit Hilfe einer Reihe von hypergeometrischen Funktionen, welche für den Fall ganzzahliger Indizes ...
openaire   +3 more sources

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