Results 131 to 140 of about 79,551 (308)
Advanced Materials Technologies, EarlyView.A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti +4 more
wiley +1 more source
, 2018 Some fluorescence microscopies, like confocal laser scanning microscopy (CLSM), have limited penetration depth. Consequently, the visualization and imaging of 3D cell cultures, such as spheroids, can be a significant challenge.
Costa, Elisabete C. +3 more
core
, 2016 Ki-67 LI (A) was measured in cultured spheroids, in vivo xenografts and implanted spheroids using ki-67 stained histological sections. A semi-quantitative scoring was performed for CD133 (B) nestin (C) and podoplanin (D). Data are shown as means ± SEM, n
Stine Skov Jensen (2889311) +9 more
core +1 more source
Advanced Materials Technologies, EarlyView.Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina +5 more
wiley +1 more source
Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications
Advanced Materials Technologies, EarlyView.This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo +2 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.In this study, we developed a light–driven soft microgripper by 3D–printing a photo–crosslinkable, temperature–responsive hydrogel with embedded silver particles onto an optical fiber tip. The microgripper actuates via photothermal effects at cell culture temperature and can gently grasp spheroids without minimal damage, offering a compact, actuator ...
Shogo Oishi +7 more
wiley +1 more source
Organoids as Building Blocks for Adaptive and Resilient Biohybrid Robots
Advanced Materials Technologies, EarlyView.ABSTRACT Biohybrid robots combine engineered living tissues with synthetic materials and have emerged as a promising class of soft robotic systems capable of mimicking biological functions such as biodegradability, energy efficiency and flexible motions. By integrating biological and synthetic components, these systems leverage complementary properties
Antonia Georgopoulou
wiley +1 more source
Frontiers in Cellular NeuroscienceMitochondrial diseases are a group of severe pathologies that cause complex neurodegenerative disorders for which, in most cases, no therapy or treatment is available.
Raquel Coronel +8 more
doaj +1 more source
Advanced Robotics Research, EarlyView.An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy +13 more
wiley +1 more source
PharmaceuticsThe phytochemical diversity and potential health benefits of V. oxycoccos and V. macrocarpon fruits call for further scientific inquiry. Our study aimed to determine the phytochemical composition of extracts from these fruits and assess their antioxidant,
Rima Šedbarė +3 more
doaj +1 more source