Results 31 to 40 of about 79,551 (308)

Extracellular matrix mediates moruloid-blastuloid morphodynamics in malignant ovarian spheroids

open access: yesLife Science Alliance, 2021
Expression dynamics of basement membrane-like extracellular matrix and fibronectin regulate transitions between solid (moruloid) and cavitational (blastuloid) phenotypes of ovarian cancer spheroids.
Jimpi Langthasa   +5 more
doaj   +1 more source

Formation of cell spheroids using Standing Surface Acoustic Wave (SSAW)

open access: yes, 2018
3D bioprinting becomes one of the popular approaches in the tissue engineering. In this emerging application, bioink is crucial for fabrication and functionality of constructed tissue.
Sriphutkiat, Yannapol   +5 more
core   +1 more source

IN VITRO INVESTIGATION OF THE TRANSPLANTATION PROSPECTS OF MULTICELLULAR SPHEROID MICROAGGREGATES OF DONOR RETINAL PIGMENT EPITHELIUM

open access: yesВестник трансплантологии и искусственных органов, 2015
Aim. To study in experiment the criteria for transplantability of multicellular spheroid microaggregates of retinal pigment epithelium (RPE), prepared by the method of 3D cell culture. Materials and Methods. 11 donor eyes (6 of adrenaline index «A», 5 of
S. A. Borzenok   +3 more
doaj   +1 more source

Assembly of breast cancer heterotypic spheroids on hyaluronic acid coated surfaces

open access: yes, 2017
Drug screening is currently demanding for realistic models that are able to reproduce the structural features of solid tumors. 3D cell culture systems, namely spheroids, emerged as a promising approach to provide reliable results during drug development.
Correia, I.J.   +5 more
core   +1 more source

Morphology of single cell type spheroids and composite spheroids.

open access: yes, 2012
Representative phase contrast images of multicellular spheroids generated by the hanging drop method after 4 days in culture. MEFs, mouse embryonic fibroblasts.
Tine V. Karlsen (148379)   +6 more
core   +1 more source

Successful Delivery of Small Non-Coding RNA Molecules into Human iPSC-Derived Lung Spheroids in 3D Culture Environment

open access: yesBiomedicines
Background/Objectives: Spheroid cultures in Matrigel are routinely used to study cell behaviour in complex 3D settings, thereby generating preclinical models of disease.
Anja Schweikert   +7 more
doaj   +1 more source

Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing. [PDF]

open access: yesPLoS ONE, 2017
It has been suggested that chemoresistance of chondrosarcoma (CHS), the cartilage tumor, is caused by the phenotypic microenvironmental features of the tumor tissue, mainly the chondrogenic extracellular matrix (ECM), and hypoxia.
Aurélien Voissiere   +6 more
doaj   +1 more source

Advanced spheroidal degeneration [PDF]

open access: yesDigital Journal of Ophthalmology, 2019
Spheroidal degeneration, involving the cornea and/or the conjunctiva, is characterized by amber-colored homogeneous, translucent spherules in the corneal stroma, Bowman’s membrane, and subepithelium. The condition has a higher prevalence in areas with extreme temperatures, low humidity, high wind, and presence of sand.
Abdelrahman M, Elhusseiny   +5 more
openaire   +2 more sources

PCA plot depicting the variance between the gastric cancer spheroids and normal gastric spheroids.

open access: yes, 2016
PCA plot depicting the variance between the gastric cancer spheroids and normal gastric spheroids.
Gokula Krishnan Ramachandran (3111387)   +2 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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