Results 201 to 210 of about 68,956 (338)

A Microfluidic Platform for Actin‐Based Membrane Remodeling Reveals the Stabilizing Role of Branched Actin Networks on Lipid Microdomains

Small Science, EarlyView.
A microfluidic assay to study actin‐driven shape changes of giant unilamellar vesicles (GUVs) is developed. This system enables high‐throughput analysis of membrane remodeling and reveals how actin networks and lipid domains influence each other. It offers a powerful tool to dissect membrane deformation mechanisms in controlled environments. Cell shape
Lixin Huang, Rogério Lopes Dos Santos, Sid Labdi, Guillaume Lamour, Olek Maciejak, Michel Malo, John Manzi, Martin Lenz, Jacques Fattaccioli, Clément Campillo   +9 more
wiley   +1 more source

Sphingolipids are essential for the growth of Chinese hamster ovary cells. Restoration of the growth of a mutant defective in sphingoid base biosynthesis by exogenous sphingolipids.

, 1992
Kentaro Hanada, Masahiro Nishijima, M. KISO, Ayaka Hasegawa, Shushi Fujita, Tomohisa Ogawa, Y Akamatsu   +6 more
openalex   +1 more source

High‐Speed Atomic Force Microscopy Reveals the Dynamic Interplay of Membrane Proteins is Lipid‐Modulated

Small Science, EarlyView.
High‐speed atomic force microscopy captures the lipid‐dependent clustering dynamics of pentameric FocA and tetrameric GlpF in supported lipid bilayers. Protein mobility, cluster stability, and packing geometry vary with lipid composition, revealing how membrane environments regulate supramolecular membrane protein organization.
Eunji Shin, Yining Jiang, Batiste Thienpont, James N Sturgis, Simon Scheuring   +4 more
wiley   +1 more source

A comprehensive analysis through Mendelian randomization of immunological markers and sphingolipid metabolism. [PDF]

Discov Oncol
Yang D, Zhang W, Wang Q.
europepmc   +1 more source

Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity

, 1992
William J. Pinto, Greg Wells, Robert L. Lester   +2 more
openalex   +1 more source

Sphingolipid Biosynthesis de Novo by Rat Hepatocytes in Culture. [PDF]

, 1995
Alfred H. Merrill, Susanne Lingrell, Elaine Wang, Mariana Nikolova‐Karakashian, Teresa R. Vales, Dennis E. Vance   +5 more
openalex   +1 more source

Multi‐Omics Analysis of Ileal Mucosa and Mesentery Before and After Ileocecal Resection in Crohn's Disease

United European Gastroenterology Journal, EarlyView.
ABSTRACT Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is a chronic disorder involving any part of the gastrointestinal tract. Ileocecal resection may serve as a more effective treatment option for early CD. However, the potential relationship and mechanisms between the ileocecum and remission induction of CD are still elusive.
Kai Xia, Yiran Jiao, Luoqiu Zhang, Renyuan Gao, Fangtao Wang, Yun Pan, Shuang Cui, Yin Lin, Tianqi Wu, Lin Li, Xiaocai Wu, Yu Ruan, Jing Sun, Lu Yin, Chunqiu Chen, Moubin Lin   +15 more
wiley   +1 more source

Single-cell transcriptome sequencing reveals the sphingolipid metabolism pathway plays an important role in leaf senescence in tobacco. [PDF]

BMC Plant Biol
Sun Q, Hou B, Liu X, Zhang L, Chang P, Pang H, He X, Huang Z, Zhang J, Liu G, Gong D, Chen M.   +11 more
europepmc   +1 more source

Activation of the de novo Biosynthesis of Sphingolipids Mediates Angiotensin II Type 2 Receptor-induced Apoptosis [PDF]

, 1999
Jukka Lehtonen, Masatsugu Horiuchi, Laurent Daviet, Masahiro Akishita, Victor J. Dzau   +4 more
openalex   +1 more source

Microglial States Are Susceptible to Senescence and Cholesterol Dysregulation in Alzheimer's Disease

Aging Cell, EarlyView.
Senescent microglia in Alzheimer's disease exhibit dysregulated cholesterol metabolism and express Disease‐Associated Microglia (DAM) signatures, including inflammatory and phagocytic markers. Single‐nucleus RNA‐seq from human brain tissues identified cholesterol‐related senescence gene co‐expression modules linked to microglial senescence.
Boyang Li, Shaowei Wang, Bilal Kerman, Cristelle Hugo, E. Keats Shwab, Chang Shu, Ornit Chiba‐Falek, Zoe Arvanitakis, Hussein N. Yassine   +8 more
wiley   +1 more source