Results 181 to 190 of about 52,400 (306)
Intersection of Sphingolipid and Sterol Metabolism at the Level of Orm Proteins in Yeast. [PDF]
Barone F +5 more
europepmc +1 more source
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri +13 more
wiley +1 more source
Ceramides in the Heart: Physiological and Pathological Roles and Regulation. [PDF]
Chen X, Fonseka O, Han Y, Liu W.
europepmc +1 more source
Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells
Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski +3 more
wiley +1 more source
Effects of Different Initial pH Conditions on the Antioxidant Capacity and Lipidomic Profiles of <i>Samsoniella hepialid</i>. [PDF]
Tong Y +6 more
europepmc +1 more source
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
Mediation of sphingolipid metabolism on the relationship between human nitrosamines exposure and esophageal cancer risk. [PDF]
Zhao C +15 more
europepmc +1 more source
Enhancing IR‐MALDESI MSI Spatial Resolution Through Beam Constriction With a Ring‐Actuated Iris
ABSTRACT Rationale Infrared matrix‐assisted laser desorption electrospray ionization (IR‐MALDESI) mass spectrometry imaging (MSI) enables label‐free, spatially resolved molecular analysis of biological tissues under ambient conditions. While improving spatial resolution is important for mapping fine tissue structures, mid‐infrared (IR) lasers are ...
Sarah M. Ashbacher +6 more
wiley +1 more source
Plasma Sphingolipid Profiling Predicts Radiosensitivity in Hepatocellular Carcinoma. [PDF]
Yuan X +8 more
europepmc +1 more source

