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Biochemistry (Moscow), 2008
The role of sphingolipids as receptors of bacteria, viruses, and toxins and also as ligands of proteinaceous receptors involved in the cell-cell signaling in animals is considered.
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The role of sphingolipids as receptors of bacteria, viruses, and toxins and also as ligands of proteinaceous receptors involved in the cell-cell signaling in animals is considered.
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The Genetics of Sphingolipid Hydrolases and Sphingolipid Storage Diseases
2013The relationship of sphingolipids with human disease first arose from the study of sphingolipid storage diseases over 50 years ago. Most of these disorders are due to inherited deficiencies of specific sphingolipid hydrolases, although a small number also result from defects in sphingolipid transport or activator proteins.
Edward H, Schuchman +1 more
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2023
Sphingolipids are a class of lipids containing the backbone of long-chain amino-alcohol bases in their structure, which are synthesized in the endoplasmic reticulum. Modification of this base gives rise to a variety of such lipids ranging from simple to complex sphingolipids that play a significant structural and functional role in membrane biology as ...
Shaista Nosheen +3 more
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Sphingolipids are a class of lipids containing the backbone of long-chain amino-alcohol bases in their structure, which are synthesized in the endoplasmic reticulum. Modification of this base gives rise to a variety of such lipids ranging from simple to complex sphingolipids that play a significant structural and functional role in membrane biology as ...
Shaista Nosheen +3 more
openaire +1 more source
Gene Therapy of Sphingolipid Metabolic Disorders
International Journal of Molecular Sciences, 2023Alisa Shaimardanova +2 more
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Sphingosine‐1‐phosphate controls endothelial sphingolipid homeostasis via ORMDL
EMBO Reports, 2023Linda Sasset +2 more
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Cholesterol and Sphingolipid Enriched Lipid Rafts as Therapeutic Targets in Cancer
International Journal of Molecular Sciences, 2021Maria De Las Mercedes Garcia Gil +2 more
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