Lifespan trajectories of serum sphingolipids in a clinically healthy Swiss population, towards precision medicine in cardiometabolic health assessment. [PDF]
Carrard J +9 more
europepmc +1 more source
Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez +1 more
wiley +1 more source
Sphingolipid homeostasis and dysregulation in liver function and disease. [PDF]
Lan J +7 more
europepmc +1 more source
Abstract Seafood provides an essential source of macro‐ and micronutrients for coastal communities worldwide. Climate change is a key threat to seafood security, altering the sizes, abundances, distributions, physiology and ecological interactions of fisheries species, and increasingly, there is evidence of impacts to seafood nutritional quality.
Tanika C. Shalders +6 more
wiley +1 more source
Evolutionary diversity of sphingolipid metabolism proteins in fungi. [PDF]
Płecha M +8 more
europepmc +1 more source
Pan‐genome analysis reveals that high‐altitude Rhododendron species resist alpine cold stress by rapidly sensing and engaging the chilling response pathway and genes that directly and indirectly protect the plant from UV radiation. Heritable genomic features such as long terminal repeats contribute to the adaptive diversification of Rhododendron ...
Haoyang Zhou +11 more
wiley +1 more source
Decoding the Sphingolipid Landscape of Clear Cell Renal Cell Carcinoma: A Single-Cell-Guided Prognostic Model Built With 101 Machine Learning. [PDF]
Huang J +9 more
europepmc +1 more source
The algal homolog of the plant CER1 and CER3 proteins is a bifunctional hydrocarbon‐forming enzyme
Schematic representation of the proposed reactions carried out by a CER1/3 protein from green algae. CoA, coenzyme A; CTD, C‐terminal domain; Cys, catalytic cysteine of C‐terminal domain; His, catalytic histidines of N‐terminal domain; NTD, N‐terminal domain.
Ángel Baca‐Porcel +9 more
wiley +1 more source
Sphingolipids and Mortality in Hemodialysis: Innocent Bystanders or Causal Culprits? [PDF]
Saum KL, Pennathur S.
europepmc +1 more source
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz +8 more
wiley +1 more source

