Results 211 to 220 of about 48,095 (292)

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

Photochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio, Sanjay Anand, Jeffrey B. Travers, Edward V. Maytin, Craig A. Rohan   +4 more
wiley   +1 more source

Myristic Acid Remodels Sphingolipid Metabolism via Dual Pathways: Canonical d18-Sphingolipid Regulation and Non-Canonical d16-Sphingolipid Synthesis. [PDF]

Nutrients
You Y, Zeng Q, Hu Z, Chen Y, Zhan M, Wang Y, Duan J.   +6 more
europepmc   +1 more source

Integration of network pharmacology, metabolomics and lipidomics for clarifying the role of sphingolipid metabolism in the treatment of liver cancer by regorafenib

Hua Mu, Jinlong Hu, Zhikun Lin, Letian Wei, Qi Li, Xiaolin Wang, Pengyu Geng, Rui Zhong, Shimeng Cui, Wenru Liu, Chunxiu Hu, Guowang Xu, Guang Tan   +12 more
openalex   +1 more source

Longitudinal metabolomics study of phosphate‐adenine‐guanosine‐glucose‐saline‐mannitol stored red blood cells

Transfusion, EarlyView.
Abstract Background The storage of red blood cells (RBCs) is essential for transfusion but leads to storage lesions that compromise RBC quality and increase the risk of transfusion‐related adverse effects, including allergic transfusion reactions (ATRs). Understanding storage‐induced metabolic change is crucial for enhancing transfusion safety.
Gürkan Bal, Maia Dzamashvili, Zhuoran Li, Magda Babina, Nidal Toman, Abdulgabar Salama   +5 more
wiley   +1 more source

Dihydroquercetin Attenuates Silica-Induced Pulmonary Fibrosis by Modulating the Gut Microbiota and the Serum Metabolites in Mice. [PDF]

Food Sci Nutr
Ke Z, Lin L, Long Y, Zhang W, Guo J, Yuan L.   +5 more
europepmc   +1 more source

Glial cells in the heart: Implications for their roles in health and disease

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya, Rimma Dugarova, Shefeeq M. Theparambil   +2 more
wiley   +1 more source

Sphingomyelin synthase-related protein is a regulator of serine palmitoyltransferase. [PDF]

J Lipid Res
Li X, Li Z, Chiang YP, Worgall T, Souaiaia T, Jiang XC.   +5 more
europepmc   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source

Metabolic Landscape of Endometrial Cancer: Insights into Pathway Dysregulation and Metabolic Features. [PDF]

Biomedicines
Yang Q, Tian X, Hu M, Ma W, Xie Q, Liu J, Hong L.   +6 more
europepmc   +1 more source

The role of vitamin D receptor signaling in hair follicle health and alopecia: Current understanding and therapeutic implications

Journal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
The vitamin D receptor (VDR) regulates hair follicle biology through ligand‐dependent and ligand‐independent mechanisms by heterodimerizing with retinoid X receptor, recruiting coactivator complexes, and activating target genes including Wnt inhibitors, hair keratins, and cell cycle regulators.
Liancheng Guan, Fan Yang, Meijuan Li, Yujia Chen, Zexin Zhao, Hongxia Li, Deping Luo, Qian Li, Yunzhi Chen   +8 more
wiley   +1 more source