Results 231 to 240 of about 48,095 (292)

The role of cytokines in ovarian cancer drug resistance

International Journal of Cancer, Volume 158, Issue 4, Page 821-834, 15 February 2026.
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang, Yunxia Zang, Rebeka Dejenie, Junyuan Bing, Shixia Dong, Yanfei Zhang, Yi Zhu, Jingjing Li   +7 more
wiley   +1 more source

Bone marrow-derived mesenchymal stem cells alleviate hepatic lipid metabolism disorders after scald injury: integrating liver transcriptome and metabolome. [PDF]

Stem Cell Res Ther
Chen Z, Yang Y, Shi X, Yang R, Fang W, Liang G, Li Y, Gao J, Ma L, Yang J, Pang R.   +10 more
europepmc   +1 more source

Bioactive Sphingolipids of Cordyceps sinensis Modulate Tumor Immunity Through the SphK1 ‐Mediated Cer/ S1P Axis [PDF]

Qi‐Xuan Kuang, Chen‐Yi Yan, Chao‐Yu Wang, Yunjie Hu, Y. Q. Huang, Hao‐Ran Lei, Peng Wan, Yi‐Fang Jiang, Fu Xi, Da‐Le Guo, Xiaofeng Li, Feng‐Ming You, Yun Deng   +12 more
openalex   +1 more source

Placental Protein Release and Uptake From the Fetal Circulation in Healthy Term Pregnancies—A Human In Vivo Exploratory Study

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Fetal‐placental communication was explored by comparing protein abundances in paired umbilical artery and vein samples, using the SomaLogic 5000‐plex platform. 766 proteins were identified as released by the placenta, largely supported by placental gene expression patterns reported in transcriptomic studies.
Hilde Bastøe Sellevoll, Ina Jungersen Andresen, Ane Cecilie Westerberg, Maren‐Helene Langeland Degnes, Thor Ueland, Manuela Zucknick, Trond Melbye Michelsen   +6 more
wiley   +1 more source

Epigenetic silencing of SPHK1-IRF7 axis drives inflammaging in age-related meniscus degeneration via sphingolipid-immune dysregulation. [PDF]

J Orthop Surg Res
Yang S, Wang H, Wang L, Liu L, Xu P, Tian X, Chen G.   +6 more
europepmc   +1 more source

Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes

Advanced Therapeutics, Volume 9, Issue 2, February 2026.
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava, Lydia Herrmann, Eden Ozkan, Abhiram Kunamneni, Vinamra Swaroop, Geetika Nehra, Rohit Srivastava, Pratima Tripathi, Ken Inoki, Julie E. Goodwin   +9 more
wiley   +1 more source

Bovine Milk Polar Lipids: Lipidomics Advances and Functional Perspectives. [PDF]

Foods
Fappani G, Liu Z, Rochfort S, Rocchetti G.   +3 more
europepmc   +1 more source

Metabolite Profiling and Anticancer Evaluation of Iraqi Haloxylon articulatum Halophyte via LC–HRMS/MS, Molecular Docking, and ADMET Analysis

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
This study investigates the phytochemical composition and biological activities of a hydroalcoholic extract of Haloxylon articulatum. LC‐HRMS/MS identified diverse bioactive compounds, notably N‐caffeoyltyramine and sinapoyltyramine. The extract exhibited strong antioxidant activity and significant cytotoxic effects against gastric cancer cell lines ...
Jihen Abidi, Amal Ben Hassena, Rania Ben Hmida, Łukasz Kulinowski, Erdi Can Aytar, Reyedh R. Al‐Rashidi, Mohamed Bouaziz   +6 more
wiley   +1 more source

Spatial metabolomics atlas in the progression of oral squamous cell carcinoma. [PDF]

J Transl Med
Zhao H, Han W, Shi C, Luo G, Lu W, Fu Y, Hu Q, Song X, Shang Z, Yang X.   +9 more
europepmc   +1 more source

The emerging role of CAMK1D in diabetes, metabolism and feeding behaviours: A mechanistic systematic review

Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.
This systematic review synthesizes evidence from published studies, GWAS and grey literature (patents) to show that CAMK1D is implicated in diabetes, obesity, insulin resistance and altered feeding behaviours, with diagnostic potential and mechanistic relevance through regulatory binding and tissue‐specific effects.
Livio Tarchi, Annalisa Di Giacomo, Lorenzo Bonacchi, Andrea Di Santo, Paolo Rovero, Chiara Sassoli, Rachele Garella, Roberta Squecco, Gianluca Villa, Romina Nassini, Francesco De Logu, Tiziana Pisano, Valdo Ricca, Giovanni Castellini   +13 more
wiley   +1 more source