Results 51 to 60 of about 1,761,902 (161)

Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders

, 2010
Sphingolipids are polar membrane lipids present as minor components in eukaryotic cell membranes. Sphingolipids are highly enriched in nervous cells, where they exert important biological functions.
M. Piccinini, Nicoletta Loberto, A.E.G. Prinetti, Barbara Buccinnà, Federica Scandroglio, Marco Piccinini, F. Scandroglio, Giovanni DeMarco, Vanna Chigorno, Elisa Lupino, S. Sonnino, E. Lupino, M. Aureli, Sandro Sonnino, Alessandro Prinetti, S. Prioni, Annarosa Lomartire, M. Rinaudo, Maria Teresa Rinaudo, N. Loberto, A. Lomartire, Massimo Aureli, Simona Prioni, V.L. Chigorno, B. Buccinà, G. De Marco, Piccinini, Marco, De Marco, Giovanni, Buccinna', Barbara, Lupino, Elisa, Rinaudo, Maria Teresa, Lomartire, Annarosa   +31 more
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Identification of novel sphingolipid-binding motifs in mammalian membrane proteins

Specific interactions between transmembrane proteins and sphingolipids is a poorly understood phenomenon, and only a couple of instances have been identified.
Brügger, Britta, Ernst, Andreas, von Heijne, Gunnar,, Björkholm, Patrik,, Hacke, Moritz, Wieland, Felix   +5 more
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Sphingolipid trafficking - Sorted out?

, 1992
Studies of intracellular membrane traffic have traditionally focused on the protein components of membranes, but what about lipids? Recent findings have drawn attention to the transport of one type of lipid, the sphingolipids.
Burger, K.N.J., van Meer, G., Dep Biologie, Universiteit Utrecht, Dep Scheikunde, Membrane Enzymology   +5 more
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Endosome and Golgi‐associated degradation ( EGAD ) of membrane proteins regulates sphingolipid metabolism

, 2019
International audienceCellular homeostasis requires the ubiquitin-dependent degradation of membrane proteins. This was assumed to be mediated exclusively either by endoplasmic reticulum-associated degradation (ERAD) or by endosomal sorting complexes ...
Oliver Schmidt, Peter, Matthias,, Peter, Matthias, H, Angelova, Mihaela, Fröhlich, Florian, Sebastian Eising, Baumann, Verena, Weyer, Yannick, Schleiffer, Alexander, Peter, Matthias, Widerin, Michael,, Teis, David, Widerin, Michael, A, Schmidt, Oliver, Lindner, Herbert, Matthias Peter, Yannick Weyer, Mihaela Angelova, Herbert Lindner, Michael A Widerin, Kremser, Leopold, Leopold Kremser, Verena Baumann, Alexander Schleiffer, Widerin, Michael A., Florian Fröhlich, Eising, Sebastian, David Teis, Weyer Y, Peter M, Teis D, Schmidt O, Eising S, Kremser L, Angelova M, Fröhlich F, Widerin MA, Lindner H, Schleiffer A, Baumann V   +39 more
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Inflammatory response and its relation to sphingolipid metabolism proteins: Chaperones as potential indirect anti-inflammatory agents

, 2019
Lysosome is the organelle responsible for breaking down macromolecules to maintain homeostasis and to fight infection. The disruption of normal lysosomal function due to mutations in the sphingolipid metabolism proteins leads to a class of lysosomal ...
Hatice Asuman Ozkara, Yagci, Z. Begum, Z. Begum Yagci, Elif Esvap, Elif Ozkirimli Olmez, ÖZKIRIMLI ÖLMEZ, ELİF, ÖZKARA, HATİCE ASUMAN, Olmez, Elif Ozkirimli, Esvap, Elif, Kutlu O. Ulgen, Ulgen, Kutlu O.   +10 more
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Sphingolipid-Binding Domain in the Serotonin1A Receptor

, 2012
Sphingolipids are essential components of eukaryotic cell membranes and are responsible for important cellular functions. A characteristic feature of sphingolipid organization in cellular membranes is their segregation in membrane domains.
Fantini, Jacques, Yamuna Devi Paila, Paila, Yamuna Devi, Shrivastava, Sandeep, Sandeep Shrivastava, Shrish Tiwari, Chattopadhyay, Amitabha, Amitabha Chattopadhyay, Tiwari, Shrish, Pushpendra Singh, Jacques Fantini, Singh, Pushpendra   +11 more
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Sphingolipid transport

, 2010
Sphingolipids are a family of ubiquitous membrane components that exhibit multiple functional properties fundamental to cell properties. Sphingolipid transport represents a crucial aspect in the metabolism, signaling and biological role of sphingolipids.
P. Giussani, P. Viani, Paola Viani, Laura Riboni, L. Riboni, Paola Giussani   +5 more
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Sphingolipid domains in the plasma membrane of fungal cells : Interplay with membrane proteins and antifungal resistance

, 2022
Plasma membrane (PM) carries out multiple functions a tightly regulated dynamic organization into specialized domains of different size, stability, and composition.
Santos, Filipa C.
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Plasminogen activator inhibitors

, 1987
Chemicals/CAS: fibrin, 9001-31-4; plasminogen activator inhibitor, 105844-41-5; plasminogen activator, 9039-53-6; Carrier Proteins; Glycoproteins; Plasminogen Activators, EC 3.4.21.-; Plasminogen Inactivators; Protease Inhibitors; protease ...
Sprengers, E.D., Kluft, C.
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Use of photoactivatable sphingolipid analogues to monitor lipid transport in mammalian cells

, 1997
Photoactivatable derivatives of ceramide, glucosylceramide (GlcCer) and sphingomyelin {3-(p-azido-m-[I-125]iodophenyl)propionylceramide, 3-(p-azido-m-[I-125]iodophenyl)propionyl-GlcCer and 3-(p-azido-m-[I-125]iodophenyl)propionylsphingomyelin} were ...
Hoekstra, D, Zegers, MMP, Kok, JW
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