The Role of Lipid Metabolism in the Progression of Breast Cancer. [PDF]
Liu TT, Wang MM.
europepmc +1 more source
ABSTRACT Vision impairment caused by age‐related macular degeneration (AMD) is a global health priority. Retinal pathology is driven by ageing and exacerbated by genetic and environmental risk factors. Peripheral blood circulation is increasingly recognised as a contributor to disease initiation and progression, and a source of biomarkers to support ...
Marzena Kurzawa‐Akanbi +17 more
wiley +1 more source
Lithium ameliorates neural differentiation restoring cell death balance in Cornelia de Lange syndrome 2D and 3D models. [PDF]
Parodi C +20 more
europepmc +1 more source
Metabolic Syndrome: From Mechanisms to Therapeutic Interventions
A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
wiley +1 more source
Multi-omics analyses reveal novel metabolic signatures of post-traumatic deep vein thrombosis in patients with coronary heart disease. [PDF]
Aliyu M +7 more
europepmc +1 more source
Comprehensive DIA‐MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice
ABSTRACT Soil salinity severely affects rice growth, yield, and quality, posing a global food security challenge. Rice is particularly vulnerable to high salinity, which restricts growth and tolerance to other stresses. To address this, breeding efforts have been made in the past, leading to the generation of multi‐stress‐tolerant rice lines.
Cheol Woo Min +8 more
wiley +1 more source
Multi-omics reveal phosphatidic acid phosphatases modify Niemann-Pick type C disease severity. [PDF]
Munkacsi AB +19 more
europepmc +1 more source
Free Fatty Acids Carried by Lipoproteins: Revisiting the Overlooked Cargo
ABSTRACT Free fatty acids (FFAs) are hydrophobic and therefore cannot enter the bloodstream at appreciable levels unless they are solubilized by FFA carriers. Albumin has been appreciated for years as the major FFA carrier, but it is not the only carrier.
Gregory C. Henderson +2 more
wiley +1 more source
Dysregulation of sphingolipid-metabolizing enzymes in Friedreich's ataxia: <i>In vitro</i> and <i>in vivo</i> insights into therapeutic targeting. [PDF]
Ramchunder Z +10 more
europepmc +1 more source
This manuscript systematically elucidates the molecular mechanisms underlying absorption, transport, and metabolism of Astaxanthin in aquatic animals, through the analysis of biological functions, transport proteins, and enzyme metabolism system. Furthermore, it outlines future molecular research strategies for Astaxanthin, providing a theoretical ...
Huakang Peng +12 more
wiley +1 more source

