Results 141 to 150 of about 1,665,622 (222)

Metabolomic Insights into Lysosomal Storage Diseases: An Untargeted View. [PDF]

Metabolites
Di Carlo G, Tommolini ML, Frisco A, Spalluto G, Foley D, Zucchelli M, Cufaro MC, Cicalini I, Bucci I, Federici L, De Laurenzi V, Pieragostino D, Rossi C.   +12 more
europepmc   +1 more source

Functional Specialization of Clathrin‐Independent Endocytic Routes: Mechanisms and Cellular Roles

Traffic, Volume 27, Issue 3, September 2026.
Distinct clathrin‐independent endocytic (CIE) routes support specialized cellular functions across different contexts. Created with Biorender.com. ABSTRACT Clathrin‐independent endocytosis (CIE) comprises a diverse repertoire of internalization mechanisms that operate in parallel with clathrin‐mediated endocytosis.
Andrea Francesco Benvenuto, Amir Fardin, Matteo Balestra, Pier Paolo Di Fiore, Chiara Tordonato, Sara Sigismund   +5 more
wiley   +1 more source

Metabolic Perspective on Atherosclerosis: Macrophage Reprogramming and Novel Therapeutic Targets. [PDF]

J Am Heart Assoc
Wang Z, Zhang Y, Li L, Wang Z.
europepmc   +1 more source

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

Veterinary and Comparative Oncology, Volume 24, Issue 3, Page 468-484, September 2026.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri, Amornthep Kingkaw, Nawarus Prapaiwan, Rangsima Sujittosakul, Nichapat Iamkaewprasert, Jiraschaya Piputwat, Puetta Isama‐al, Thanutchanok Munkongdee, Thanapon Chotikaprakal, Petchpailin Yanyongsirikarn, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Parichart Tesena   +13 more
wiley   +1 more source

ORMDL Proteins Turnover via Proteasome and Autophagy Is Cell-Type Dependent and Tied to Ceramide Homeostasis. [PDF]

FASEB J
Mrkacek M, Tumova M, Puskasu A, Utekal P, Vrbacky M, Kuchar L, Draber P, Bugajev V.   +7 more
europepmc   +1 more source

Impact of aging on neck vasculature and brain biochemistry in female mice

Physiological Reports, Volume 14, Issue 17, September 2026.
Abstract Age‐related changes in large‐vessel biomechanics may contribute to neurovascular dysfunction and region‐specific biochemical remodeling in the brain, with important implications for female health. This study investigated the impact of aging on neck vasculature and brain lipid biochemistry in female C57BL/6NHsd mice by comparing young (12 weeks;
Allison R. Jones, Amin Jarrahi, Kylee Karpowich, EllaGrey Moody, Lily Renner, Lindsay P. Brown, Caitlin M. Tressler, A. Colleen Crouch   +7 more
wiley   +1 more source

The Involvement of Ceramide, Sphingosine-1-Phosphate and Ganglioside GM1 in Regulating Some Nervous System Functions. [PDF]

Int J Mol Sci
Giussani P, Mauri L, Sonnino S.
europepmc   +1 more source

Mimicking Cellular Membranes With Micropatterned Lipid Bilayers

ChemPhysChem, Volume 27, Issue 16, 27 August 2026.
This Perspective spotlights micropatterning of as a key tool to model membrane systems which capture the complexities of cellular membranes, specifically of bacterial ones. Through precise manipulation of compositional heterogeneity, morphology, and topography in artificial bilayers, these synthetic membranes serve as in vitro analogs of cellular ...
Thuy An Nguyen, Zexi Xu, Petra Schwille
wiley   +1 more source

<i>ORMDL3</i>: from an asthma susceptibility gene to multi-disease associations. [PDF]

Front Genet
Han Z, Guo S, Wang C, Niu Y, Liu J, Li K, Li D, Yu F, Li X.   +8 more
europepmc   +1 more source

Lipid metabolic dysregulation in diabetic kidney disease: mechanisms, cellular impact, and therapeutic strategies. [PDF]

J Clin Transl Endocrinol
Wang Y, Wu L, Bao X, Yang J, Xu M, Chang Y, Liu Z, Qin L, Gao M, Lv C, Liu T.   +10 more
europepmc   +1 more source