Tissue‐Resident Macrophage in Inflammation and Cancer
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang +13 more
wiley +1 more source
The Role of Lipid Metabolism in the Progression of Breast Cancer. [PDF]
Liu TT, Wang MM.
europepmc +1 more source
Comprehensive DIA‐MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice
ABSTRACT Soil salinity severely affects rice growth, yield, and quality, posing a global food security challenge. Rice is particularly vulnerable to high salinity, which restricts growth and tolerance to other stresses. To address this, breeding efforts have been made in the past, leading to the generation of multi‐stress‐tolerant rice lines.
Cheol Woo Min +8 more
wiley +1 more source
Lithium ameliorates neural differentiation restoring cell death balance in Cornelia de Lange syndrome 2D and 3D models. [PDF]
Parodi C +20 more
europepmc +1 more source
MicroRNA‐Mediated Placental Maladaptation in Preeclampsia Pathogenesis
Graphical representation of miRNA‐mediated placental maladaptation in preeclampsia. Under normal pregnancy conditions, balanced expression of beneficial miRNAs (miR‐126‐3p, miR‐18a/b‐5p, miR‐144‐3p, miR‐378a‐5p, and miR‐146a‐5p) promotes trophoblast proliferation, migration and invasion, spiral artery remodeling, angiogenesis, mitochondrial function ...
Sarbani Saha, Rupasri Ain
wiley +1 more source
Multi-omics analyses reveal novel metabolic signatures of post-traumatic deep vein thrombosis in patients with coronary heart disease. [PDF]
Aliyu M +7 more
europepmc +1 more source
Urotensin II receptor deletion mitigates high‐fat diet‐induced kidney injury and renal lipid remodeling. Male wild‐type (WT) and urotensin II receptor–knockout (UT KO) mice were fed a high‐fat diet (HFD; 60% kcal from fat) for 33 weeks. In cultured mouse podocytes, urotensin II (UII)–UT signaling enhanced transient receptor potential canonical 6 (TRPC6)
Praghalathan Kanthakumar +1 more
wiley +1 more source
Multi-omics reveal phosphatidic acid phosphatases modify Niemann-Pick type C disease severity. [PDF]
Munkacsi AB +19 more
europepmc +1 more source
Free Fatty Acids Carried by Lipoproteins: Revisiting the Overlooked Cargo
ABSTRACT Free fatty acids (FFAs) are hydrophobic and therefore cannot enter the bloodstream at appreciable levels unless they are solubilized by FFA carriers. Albumin has been appreciated for years as the major FFA carrier, but it is not the only carrier.
Gregory C. Henderson +2 more
wiley +1 more source
Dysregulation of sphingolipid-metabolizing enzymes in Friedreich's ataxia: <i>In vitro</i> and <i>in vivo</i> insights into therapeutic targeting. [PDF]
Ramchunder Z +10 more
europepmc +1 more source

