Results 101 to 110 of about 78,947 (270)
Interdisciplinary Medicine, EarlyView.Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi +6 more
wiley +1 more source
Composition of human serum sphingomyelins
Journal of Lipid Research, 1970 Serum sphingomyelins were analyzed by argentation chromatography of the corresponding ceramide diacetates. Six subfractions were obtained. Three of them contained 4-sphingenines in combination with saturated, trans-, or cis-monoenoic fatty acids; the remaining three contained sphingadienine, also in combination with saturated, trans-, or cis-monoenoic ...
E.L. Hirvisalo, O. Renkonen
openaire +3 more sources
Interdisciplinary Medicine, EarlyView.This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu +6 more
wiley +1 more source
Translocating the blood-brain barrier using electrostatics [PDF]
, 2012 Copyright © 2012 Ribeiro,Domingues, Freire,Santos and Castanho. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the ...
Castanho, Miguel A. R. B. +4 more
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Journal of Raman Spectroscopy, EarlyView.In this work, silver nanoparticles encapsulated within quatsome membranes have shown to preserve their plasmonic properties for at least 165 days without aggregation. These hybrid nanostructures enable strong SERS enhancement of pyrene and Prodan by confining the molecules within a few nanometers from the silver surface.
Renato Cezar Peramezza Ribeiro +10 more
wiley +1 more source
Obesity dependent metabolic signatures associated with nonalcoholic fatty liver disease progression [PDF]
, 2012 Our understanding of the mechanisms by which nonalcoholic fatty liver disease (NAFLD) progresses from simple steatosis to steatohepatitis (NASH) is still very limited.
Alonso, C +7 more
core
Studies on the compounds lipids from X-ray irradiated animal,1. [PDF]
, 1962 For the purpose to reveal the mechanism of the biological indirect action of X-rays the author has conducted the analysis of the compound lipids of the organs of the rabbits irradiated with X-rays.
Ohara, Sachiko
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Portal Hypertension &Cirrhosis, EarlyView.Cirrhosis is frequently accompanied by varying degrees of lipid profile abnormalities. This study confirms that these profiles are differentially affected by disease etiology and progressively worsen—with significant reductions in TC, HDL‐C, and LDL‐C—as liver disease severity increases. TIPS improves lipid profiles, particularly by increasing HDL‐C in
Jiamin Xu +6 more
wiley +1 more source
Small Methods, EarlyView.An in‐line PAT‐integrated ML strategy for microfluidic liposome synthesis accurately predicted particle size from formulation parameters and fluoresence sensing data. The model captured both seen and unseen conditions, demonstrating robust generalization and process control with low error.
Junghu Lee +6 more
wiley +1 more source
Effects of sphingomyelinase and sphingosine on arterial vasomotor regulation.
Journal of Lipid Research, 1996 The sphingomyelin pathway is an important signal transduction system regulating various cellular functions. However, little is known about the effect of sphingomyelin metabolites on vasomotor function.
T Murohara +5 more
doaj +1 more source