Results 101 to 110 of about 51,484 (237)
Circulating Lipoprotein Sphingolipids in Chronic Kidney Disease with and without Diabetes
Abnormalities of sphingolipid metabolism play an important role in diabetes. We compared sphingolipid levels in plasma and in isolated lipoproteins between healthy control subjects and two groups of patients, one with chronic kidney disease without ...
Maria F. Lopes-Virella +4 more
doaj +1 more source
ON THE COMPONENTS OF SPHINGOMYELIN [PDF]
openaire +2 more sources
Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl +3 more
wiley +1 more source
Review and targeted lipidomic biomarkers in atherosclerosis
Ischemic cardiovascular events (ischemic stroke, myocardial infarction) are the most common complications of cardiovascular diseases. One of the leading mechanisms of these complications is atherosclerosis.
A. A. Lomonosova +12 more
doaj +1 more source
ABSTRACT Aims Cold exposure activates brown adipose tissue (BAT) and promotes thermogenic and metabolic adaptations. While BAT activation has been linked to improved cardiometabolic health, how acute cold exposure reshapes the circulating lipidome in humans remains incompletely understood.
Yu Zhang +7 more
wiley +1 more source
Sphingomyelin regulates astrocyte activity by regulating NF-κB signaling via HDAC1/3 expression
Astrocytes comprise approximately 40% of CNS cells and have pivotal roles in brain functions. Under steady-state conditions, astrocytes maintain homeostasis in the CNS through the uptake or release of neurotransmitters.
Ryo Kadowaki +4 more
doaj +1 more source
This review reconsiders the amyloid cascade by placing lipid dynamics at its core. It shows that free lipids, governed by critical micellar concentration, act as pathological chaperones that redirect amyloid aggregation toward membrane‐damaging species.
Sofia Serravalle +6 more
wiley +1 more source
Urinary lipid metabolites and progression of kidney disease in individuals with type 2 diabetes
ObjectiveA substantial proportion of individuals with type 2 diabetes (T2D) experience a fast decline (FD) in kidney function, a high-risk phenotype not reliably identified by current clinical markers.
Yu Xiao +6 more
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley +1 more source

