Results 111 to 120 of about 62,442 (260)

Enzymatic Production of Ceramide from Sphingomyelin

, 2006
Ceramide is the key intermediate in the biosynthesis of all complex sphingolipids. Due to its major role in maintaining the water-retaining properties of the epidermis, ceramide is of great commercial potential in cosmetic and pharmaceuticals such as ...
Zhang, Long, Xu, Xuebing, Hellgren, Lars
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Cholesterol favours phase separation of Sphingomyelin

, 2001
The phase behavior of mixed lipid dispersions representing the inner leaflet of the cell membrane has been characterized by X-ray diffraction. Aqueous dispersions of phosphatidylethanolamine:phosphatidylserine (4:1 mole/mole) have a heterogeneous ...
Wolf C, Koumanov K, Wolf, C, Koumanov, K, B. Tenchov, Tenchov, B, C. Wolf, P.J. Quinn, K. Koumanov, Quinn, P J, Tenchov B, Quinn P   +11 more
core   +1 more source

Circulating Lipoprotein Sphingolipids in Chronic Kidney Disease with and without Diabetes

Biomedicines
Abnormalities of sphingolipid metabolism play an important role in diabetes. We compared sphingolipid levels in plasma and in isolated lipoproteins between healthy control subjects and two groups of patients, one with chronic kidney disease without ...
Maria F. Lopes-Virella, Samar M. Hammad, Nathaniel L. Baker, Richard L. Klein, Kelly J. Hunt   +4 more
doaj   +1 more source

ON THE COMPONENTS OF SPHINGOMYELIN [PDF]

Journal of Experimental Medicine, 1913
openaire   +2 more sources

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari, Deniz Bozdag, Elif İnce‐Erguc, Aylin Buhur, Cansin Sirin Tomruk, Suna Sabuncuoglu, Altug Yavasoglu, Hande Gurer‐Orhan   +7 more
wiley   +1 more source

Sphingomyelin regulates astrocyte activity by regulating NF-κB signaling via HDAC1/3 expression

Journal of Lipid Research
Astrocytes comprise approximately 40% of CNS cells and have pivotal roles in brain functions. Under steady-state conditions, astrocytes maintain homeostasis in the CNS through the uptake or release of neurotransmitters.
Ryo Kadowaki, Hana Hirose, Gai Takimoto, Takafumi Kohama, Hiroyuki Nakamura   +4 more
doaj   +1 more source

Comparison of methods for defatted human milk and nutrient composition: An experimental study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Human milk is considered the gold standard for infant nutrition; however, it is often discontinued in chylothorax and severe very long‐chain acyl‐CoA dehydrogenase (VLCAD) deficiency. As an alternative to complete human milk restriction, defatted human milk may be fed, though it may not fully support optimal infant growth and ...
Kristin Cheng, Gina O'Toole, Stephanie Chang, Richard Chang, John Miklavcic   +4 more
wiley   +1 more source

Urinary lipid metabolites and progression of kidney disease in individuals with type 2 diabetes

Frontiers in Endocrinology
ObjectiveA substantial proportion of individuals with type 2 diabetes (T2D) experience a fast decline (FD) in kidney function, a high-risk phenotype not reliably identified by current clinical markers.
Yu Xiao, Caifeng Shi, Songyan Qin, Aiqin He, Xiaomei Wu, Chunsun Dai, Yang Zhou   +6 more
doaj   +1 more source

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source