Results 121 to 130 of about 62,442 (260)
Review and targeted lipidomic biomarkers in atherosclerosis
Российский кардиологический журналIschemic cardiovascular events (ischemic stroke, myocardial infarction) are the most common complications of cardiovascular diseases. One of the leading mechanisms of these complications is atherosclerosis.
A. A. Lomonosova +12 more
doaj +1 more source
Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine
Phytotherapy Research, EarlyView.By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao +11 more
wiley +1 more source
Optimal sphingomyelin extraction for improved infant formula
Journal of Dairy Science: This study developed a green extraction method for sphingomyelin (SM) using ethanol combined with cooling crystallization or supercritical extraction technologies.
Manman Zhang +6 more
doaj +1 more source
Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine
Small, EarlyView.Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa +18 more
wiley +1 more source
Precisely Engineering Biomimetic Nanoparticles via Controlled Cell Membrane Coating
Small, EarlyView.Precise engineering of cell membrane‐coated nanoparticles (CMNPs) requires coordinated control over particle size, coating integrity, and membrane leaflet orientation. This review integrates key synthesis parameters, assembly strategies, and analytical methods that govern these features, revealing how structural control underpins biomimetic function ...
Jie Lay Lim +4 more
wiley +1 more source
Small, EarlyView.The interactions of self‐assembled nanocarriers with cell membranes are programmable through amphiphile design. We identify how head and tail chemistry govern distinct interaction mechanisms and introduce ΔGtransfer, a unified thermodynamic descriptor that predicts nanoparticle behaviour from simple molecular simulations.
Mahsa Nami +13 more
wiley +1 more source
TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum
Insect Science, EarlyView.RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li +8 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj +4 more
wiley +1 more source
Allergy, EarlyView.Skin tape strip lipidomic analysis revealed preexisting skin barrier lipid abnormalities at day 0 that were further exacerbated after 6 weeks of CPI treatment. Significant changes in skin (but not plasma) proinflammatory cytokines were identified in future ircAE patients after 6 weeks of CPI immunotherapy.
Taras Lyubchenko +9 more
wiley +1 more source