Exploring Regulatory Frameworks for Exosome Therapy: Insights and Perspectives
ABSTRACT Extracellular vesicles (EVs) have emerged as a promising technology for diagnostic and therapeutic applications in clinical settings over the past decade. However, their advancement is hindered by complex technological and regulatory challenges.
Qiushi Li+8 more
wiley +1 more source
Causal relationship between plasma lipidome and rosacea: a Mendelian randomization analysis. [PDF]
Wang X, Zhu Z.
europepmc +1 more source
Extracellular Vesicles From Fungal Infection in Humans: A Key Player in Immunological Responses
ABSTRACT Fungal infections cause approximately 1.6 million deaths annually. Diagnosing and treating fungal infections is difficult due to limited access to diagnostic tests and rising antifungal resistance. Extracellular vesicles (EVs) facilitate interactions between fungal cells and hosts, significantly influencing the pathogen‐host relationship ...
Caroline P. de Rezende+13 more
wiley +1 more source
Microbiota–Host Interactions: Exploring Their Dynamics and Contributions to Human Diseases
Bacterial dysbiosis results from microbiota imbalances, diet, lifestyle, and other factors that lead to conditions such as IBS, IBD, acne, dermatitis, and dental diseases. The current therapeutic approaches include probiotics, prebiotics, synbiotics, microbiota transplantation, and phage therapy.
Siau Wui Chin+3 more
wiley +1 more source
Characterization of Cholesterol-Sphingomyelin Domains and Their Dynamics in Bilayer Membranes [PDF]
A. V. Samsonov+2 more
openalex +1 more source
Small Extracellular Vesicles with a High Sphingomyelin Content Isolated from Hypertensive Diabetic db/db Mice Inhibits Calcium Mobilization and Augments Amiloride-Sensitive Epithelial Sodium Channel Activity. [PDF]
Ramsay H, Yu L, Alousi FF, Alli AA.
europepmc +1 more source
Membrane Lipid Domains Distinct from Cholesterol/Sphingomyelin-Rich Rafts Are Involved in the ABCA1-mediated Lipid Secretory Pathway [PDF]
Armando J. Mendez+4 more
openalex +1 more source
Prophages play a significant role in modulating bacterial virulence and pathogenicity. Our results suggest domestication of φSa3int prophage leads to reduced phagocytosis mediating escape of S. aureus from human innate immunity. As such, targeted identification of mobile genetic elements (MGEs) in addition to species and strain identification may lead ...
Roshan Nepal+9 more
wiley +1 more source
Altered levels of sphingolipid metabolites in serum of locally advanced rectal cancer patients: A pilot study. [PDF]
Bjelanović J+6 more
europepmc +1 more source