Results 111 to 120 of about 9,168 (223)
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
The Effects of Enzyme Pretreatment Extraction on Lipid Recovery With Normal Phase HPLC
ABSTRACT With the increasing interest in the commercialization of microalgal fermentation‐based products, sustainable and efficient oil extraction methods have been developed for manufacturing and analytical testing. Due to the variability and resilience of micro‐algae cell walls, traditional lipid extraction methods such as Folch and Bligh and Dyer ...
Zhehan Jiang +4 more
wiley +1 more source
A microfluidic nanodevice that analyses a single volume droplet of whole blood (10–50 microlitres (µL)) forms a fast and fully integrated exosome‐derived liquid biopsy. The closed system architecture involves plasma separation on chip, exosome enrichment by immunoaffinity and various size based, electrokinetic, acoustofluidic or hybridized strategies ...
Daniel Ejim Uti +7 more
wiley +1 more source
SOME OBSERVATIONS CONCERNING SPHINGOMYELIN AND SPHINGOMYELIN REINECKATE
openaire +2 more sources
Microglial morphology changes in response to damage by Aβ and aging result in significant reductions in cell surface area. Transcriptomic analyses suggest that fatty acid synthesis and triacylglycerol formation drive redistribution of surface membrane into intracellular lipid droplets.
G. William Rebeck +4 more
wiley +1 more source
Neutrophils acquire extracellular fatty acids or adipocyte‐derived lipids and store them as triglycerides, polarizing into a lipid‐laden phenotype. Lipid‐laden neutrophils are found in the peripheral blood of HFD‐fed mice and patients with MASLD. These neutrophils release extracellular vesicles enriched with triglycerides and microRNAs that deliver ...
Sanjeeb Shrestha +10 more
wiley +1 more source
ABSTRACT Remnants of erythrocyte removal from blood constitute therapeutic plasma—a water‐based solution containing mainly platelets, extracellular vesicles (EVs), protein and lipid complexes and ions. Plasma‐based therapies, including their use to accelerate wound healing in human and animal patients, are increasingly gaining prominence in ...
Adrienn Molnár +12 more
wiley +1 more source
Sphingolipids and Mortality in Hemodialysis: Innocent Bystanders or Causal Culprits? [PDF]
Saum KL, Pennathur S.
europepmc +1 more source
Metabolic Regulation of Macrophages in Health and Disease
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang +6 more
wiley +1 more source
Amino Acid and Lipid Metabolism in Cancer: Mechanisms and Therapeutic Opportunities
Amino Acid and lipid metabolism in cancer: (A) Regulation of Amino acid transportation and metabolism in cancer. (B) The core organization of lipid metabolic reprogramming in cancer and their functional consequences. ABSTRACT Metabolic reprogramming is a defining feature of cancer and a major contributor to immune escape.
Zixu Wang +4 more
wiley +1 more source

