Results 31 to 40 of about 11,288 (198)

Fatty acid composition of human brain sphingomyelins: normal variation with age and changes during myelin disorders

Journal of Lipid Research, 1965
Sphingomyelins have been isolated in almost quantitative yield from normal and pathological human nervous tissues, and their fatty acid compositions determined by gas–liquid chromatography.
Stina Ställberg-Stenhagen, Lars Svennerholm   +1 more
doaj   +1 more source

Effects of Pregnancy on Plasma Sphingolipids Using a Metabolomic and Quantitative Analysis Approach

Metabolites, 2023
Changes in the maternal metabolome, and specifically the maternal lipidome, that occur during pregnancy are relatively unknown. The objective of this investigation was to evaluate the effects of pregnancy on sphingolipid levels using metabolomics ...
Luke F. Enthoven, Yuanyuan Shi, Emily Fay, Agnes Kim, Sue Moreni, Jennie Mao, Nina Isoherranen, Rheem A. Totah, Mary F. Hebert   +8 more
doaj   +1 more source

Reorganization of platelet membrane sphingomyelins by adenosine diphosphate and ticagrelor

, 2018
IF 2.766 (2017)International audiencePlatelets are major targets for the treatment of thrombo-embolic disorders. Their plasma membrane contains specialized microdomains enriched in sphingomyelins and free cholesterol including membrane receptors.
Rabani, Vahideh, Pais de Barros, Jean-Paul, Haghighi, Fatemeh, Davani, Siamak   +3 more
core   +1 more source

Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol [PDF]

, 2018
International audienceBACKGROUND: Lipoproteins are major players in the development and progression of atherosclerotic plaques leading to coronary stenosis and myocardial infarction.
Layal Abi Farraj, Farraj, Layal Abi, Zalloua, Pierre, Pierre Zalloua, Hariri, Essa, Touboul, David, Matsuda, Fumihiko, Mark Lathrop, Le Lay, Aurelie, Abi Farraj, Layal, Lathrop, Mark, M., David Touboul, Alexandre Colleu, Hanane Kadar, Lyamine Hedjazi, Nicholson, Jeremy K, Aurelie Le Lay, Fumihiko Matsuda, Lathrop, Mark,, Brial, Francois, Colleu, Alexandre, Jeremy K. Nicholson, Dubus, Justine, Essa Hariri, Hedjazi, Lyamine, Francois Brial, Kadar, Hanane, Nicholson, Jeremy,, Justine Dubus, Dominique Gauguier, Nicholson, Jeremy, K., Lathrop, Mark, Gauguier, Dominique, Zalloua, Pierre,, Dumas, Marc-Emmanuel, Marc-Emmanuel Dumas   +35 more
core   +1 more source

Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation[S]

Journal of Lipid Research, 2009
Molecular events involved in successful embryo implantation are not well understood. In this study, we used MALDI imaging mass spectrometry (IMS) technologies to characterize the spatial and temporal distribution of phospholipid species associated with ...
Kristin E. Burnum, Dale S. Cornett, Satu M. Puolitaival, Stephen B. Milne, David S. Myers, Susanne Tranguch, H. Alex Brown, Sudhansu K. Dey, Richard M. Caprioli   +8 more
doaj   +1 more source

Liquid chromatography-mass spectrometry-based metabolomic profiling reveals sex differences of lipid metabolism among the elderly from Southwest China

BMC Geriatrics, 2023
Background The sexual dimorphism represents one of the triggers of the metabolic disparities while the identification of sex-specific metabolites in the elderly has not been achieved.
Yuan-Jun Huang, Wei Ke, Ling Hu, You-Dong Wei, Mei-Xue Dong   +4 more
doaj   +1 more source

Studies on Sphingomyelins in Human Erythrocytes and Plasma. [PDF]

, 1967
Two sphingophospholipids, that is, the fast moving and the slow moving on TLC, were separated from each other by Silica Gel G TLC of the alkali- and acid-stable phospholipids isolated from human erythrocytes and plasma.
Hiroko, Tsubono, Osamu, Minari, Masako, Akiyama, Toshio, Sakagami   +3 more
core   +1 more source

Lipid balance and chemoresistance in cancer cells

eLife
A shift in the balance between two lipids – cholesterol and sphingomyelin – makes hybrid epithelial-mesenchymal cancer cells less responsive to certain chemotherapy drugs.
Kaori Kanemaru, Yoshikazu Nakamura
doaj   +1 more source

Plasma Ceramides and Sphingomyelins in Relation to Atrial Fibrillation Risk: The Cardiovascular Health Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Ceramides exhibit multiple biological activities that may influence the pathophysiological characteristics of atrial fibrillation (AF). Whether the length of the saturated fatty acid carried by the ceramide or their sphingomyelin precursors ...
Paul N. Jensen, Amanda M. Fretts, Andrew N. Hoofnagle, Colleen M. Sitlani, Barbara McKnight, Irena B. King, David S. Siscovick, Bruce M. Psaty, Susan R. Heckbert, Dariush Mozaffarian, Nona Sotoodehnia, Rozenn N. Lemaitre   +11 more
doaj   +1 more source

Lower sphingomyelins and higher ceramides in Alzheimer's patients are independent of statin use.

, 2013
Panel A shows the differences in sphingomyelin and ceramide mass levels between AD patients and controls who were taking statins. For this comparison, P = 7×10−4 for sphingomyelins and P = 0.00054 for ceramides (Wilcoxon signed rank test).
Stephen H. Boyle (348270), Hua Cheng (317084), Rima Kaddurah-Daouk (152187), P. Murali Doraiswamy (35724), Kathleen A. Welsh-Bohmer (258166), Xianlin Han (83121), James R. Burke (258157), Steve Rozen (134498), Caroline Hellegers (35723)   +8 more
core   +1 more source