Results 11 to 20 of about 14,105 (264)
Composition of human serum sphingomyelins
Journal of Lipid Research, 1970 Serum sphingomyelins were analyzed by argentation chromatography of the corresponding ceramide diacetates. Six subfractions were obtained. Three of them contained 4-sphingenines in combination with saturated, trans-, or cis-monoenoic fatty acids; the ...
E.L. Hirvisalo, O. Renkonen
doaj +3 more sources
Different Lipid Signature in Fibroblasts of Long-Chain Fatty Acid Oxidation Disorders
Cells, 2021 Long-chain fatty acid oxidation disorders (lc-FAOD) are a group of diseases affecting the degradation of long-chain fatty acids. In order to investigate the disease specific alterations of the cellular lipidome, we performed undirected lipidomics in ...
Khaled I. Alatibi +8 more
doaj +1 more source
Cancer Medicine, 2020 Large granular lymphocyte (LGL) leukemia is a rare hematological disorder with expansion of the T‐cell or natural killer (NK) cell lineage. Signal transducer and activator of transcription 3 (STAT3) exhibits somatic activating mutations in 30%‐40% of LGL
Kristine C. Olson +8 more
doaj +1 more source
Journal of Lipid Research, 2017 Rat spermatogenic cells contain sphingomyelins (SMs) and ceramides (Cers) with very long-chain PUFAs (VLCPUFAs) in nonhydroxylated (n-V) and 2-hydroxylated (h-V) forms. How these atypical species distribute among membrane fractions during differentiation
Florencia X. Santiago Valtierra +3 more
doaj +1 more source
Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers [PDF]
, 2007 Metabolomic profiling and the integration of whole-genome genetic association data has proven to be a powerful tool to comprehensively explore gene regulatory networks and to investigate the effects of genetic variation at the molecular level.
Mittelstrass, Kirstin +17 more
core +2 more sources
Acid Sphingomyelinase Regulates the Localization and Trafficking of Palmitoylated Proteins [PDF]
, 2019 In human, loss of Acid Sphingomeylinase (ASM/SMPD1) causes Niemann-Pick Disease, type A. ASM hydrolyzes sphingomyelins to produce ceramides but protein targets of ASM remain largely unclear. ...
Kim, Yongsoon +7 more
core +2 more sources
Associations of plasma very-long-chain SFA and the metabolic syndrome in adults [PDF]
, 2018 Plasma levels of very-long-chain SFA (VLCSFA) are associated with the metabolic syndrome (MetS). However, the associations may vary by different biological activities of individual VLCSFA or population characteristics.
Brenna, Thomas J. +9 more
core +1 more source
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Correlation between metabolomic profile constituents and feline pancreatic lipase immunoreactivity
Journal of Veterinary Internal Medicine, 2022 Background Feline pancreatic lipase immunoreactivity (fPLI) is commonly used to diagnose pancreatitis in cats (FP). Untargeted metabolomics has been extensively applied in human and veterinary medicine, but no metabolomic studies regarding FP have been ...
Magdalena Maria Krasztel +5 more
doaj +1 more source
Journal of Lipid Research, 2014 Gangliosides and sulfatides (STs) are acidic glycosphingolipids (GSLs) that have one or more sialic acids or sulfate substituents, in addition to neutral sugars, attached to the C-1 hydroxyl group of the ceramide long chain base. TLC is a widely employed
Hyejung Park +2 more
doaj +1 more source