Results 141 to 150 of about 29,323 (206)

Glycochenodeoxycholic acid promotes hepatocarcinogenesis by inducing hepatic progenitor cell differentiation into cancer-associated fibroblasts via sphingosine-1-phosphate receptor 2 signalling. [PDF]

Biomark Res
Gao L, Lv G, Huang Y, Xue M, Zhang Z, Weng J, Bai H, Tao M, Luo X, Gao Y, Feng S, Hou X, Zong C, Yang X, Zhao Q, Jiang J, Zhu X, Han Z, Jiang C, Zhao D, Wei L, Sun L.   +21 more
europepmc   +1 more source

The Comparative Effectiveness and Tolerability of Sphingosine-1-Phosphate Receptor Modulators in Patients With Multiple Sclerosis: A Network Meta-Analysis of Randomized Controlled Trials. [PDF]

Ann Clin Transl Neurol
Shahzad F, Rasheed T, Siddiqui MR, Hamid H, Khalid MB, Shabbir H, Shami B, Abdullah, Ahmed SI.   +8 more
europepmc   +1 more source

The sphingosine-1-phosphate receptor 2 S1PR2 mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia. [PDF]

J Biol Chem
Chang M, Zhao M, Whang EM, Lee RA, Scott DK, Wang JC.   +5 more
europepmc   +1 more source

The novel sphingosine-1-phosphate receptor modulator KRP-203 prevents myocardial ischemia-reperfusion injury by preserving mitochondrial function through activation of the RISK and SAFE signaling pathways. [PDF]

Cell Biol Toxicol
Wu N, Wang L, Yu S, Wei X, Xu H, Xu S, Jia P, Zhang X.   +7 more
europepmc   +1 more source

Sphingosine 1-phosphate receptor 1 modulators exert neuroprotective effects in central nervous system disorders. [PDF]

Front Pharmacol
Chen S, Wu L, Lang B, Zhao G, Zhang W.
europepmc   +1 more source

Persistent Activation of Sphingosine-1-Phosphate Receptor 1 by Phytosphingosine-3,4-Cyclic Phosphate Ameliorates Sepsis by Inhibiting Hyperinflammation and Vascular Hyperpermeability. [PDF]

MedComm (2020)
Duan S, Kim SG, Bao J, Lim HJ, Kim JW, Yoon SI, Park YJ, Yun S, Kim KS, Song HR, Choi MJ, Han MK.   +11 more
europepmc   +1 more source

Sphingosine 1-phosphate receptor 1signaling in macrophages reduces atherosclerosis in LDL receptor-deficient mice. [PDF]

JCI Insight
Potì F, Scalera E, Feuerborn R, Fischer J, Arndt L, Varga G, Pardali E, Seidl MD, Fobker M, Liebisch G, Hesse B, Lukasz AH, Rossaint J, Kehrel BE, Rosenbauer F, Renné T, Christoffersen C, Simoni M, Burkhardt R, Nofer JR.   +19 more
europepmc   +1 more source

Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain. [PDF]

J Med Chem
Lang J, Zhou W, Huang T, Jiang H, Chen H, Xu S, Qiu L, Heady M, Yu Y, Brier MR, Nai YH, Guglielmetti C, Perlmutter JS, Tu Z.   +13 more
europepmc   +1 more source

Lymphopenia associated with sphingosine 1-phosphate receptor modulators (S1PRMs) in multiple sclerosis: analysis of European pharmacovigilance data. [PDF]

Pharmacol Rep
Balzano N, Di Napoli R, Fraenza F, Di Giulio Cesare D, Moreggia O, Cardillo M, Scavone C, Maniscalco GT, Capuano A, Sportiello L.   +9 more
europepmc   +1 more source

Sphingosine-1-Phosphate Receptor 2 Promotes Renal Microvascular Constriction and Kidney Injury Following Renal Ischemia-Reperfusion in Rats. [PDF]

Function (Oxf)
Guan Z, Remedies CE, Zhang Y, Sanders PW, Inscho EW, Feng W.   +5 more
europepmc   +1 more source